The multicopy appearance of a large inverted duplication and the sequence at the inversion joint suggest a new model for gene amplification.
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Mechanisms of gene duplication and amplificationInverted repeats as genetic elements for promoting DNA inverted duplication: implications in gene amplificationFormation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania.Chromosomal Replication Complexity: A Novel DNA Metrics and Genome Instability FactorTransposition of the autonomous Fot1 element in the filamentous fungus Fusarium oxysporumThe molecular basis of color vision in colorful fish: four long wave-sensitive (LWS) opsins in guppies (Poecilia reticulata) are defined by amino acid substitutions at key functional sitesDNA rearrangement mediated by inverted repeats.A novel gene amplification system in yeast based on double rolling-circle replication.Induction of DNA amplification in the Bacillus subtilis chromosomeCo-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplificationRsaI repetitive DNA in Buffalo Bubalus bubalis representing retrotransposons, conserved in bovids, are part of the functional genes.The effects of insertions on mammalian intrachromosomal recombinationShort inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells.Structural features of transposed human VK genes and implications for the mechanism of their transpositionsFormation of large palindromic DNA by homologous recombination of short inverted repeat sequences in Saccharomyces cerevisiaeThe structure and early evolution of recently arisen gene duplicates in the Caenorhabditis elegans genome.Amplification of the ribonucleotide reductase small subunit gene: analysis of novel joints and the mechanism of gene duplication in vaccinia virusMYCN is retained in single copy at chromosome 2 band p23-24 during amplification in human neuroblastoma cells.Elements which stimulate gene amplification in mammalian cells: role of recombinogenic sequences/structures and transcriptional activationIn vitro evolution of terminal protein-containing genomesInduction of circles of heterogeneous sizes in carcinogen-treated cells: two-dimensional gel analysis of circular DNA molecules.Chromosomal destabilization during gene amplification.Evolution and stability of chromosomal DNA coamplified with the CAD geneMolecular structure and evolution of double-minute chromosomes in methotrexate-resistant cultured mouse cellsFormation of an inverted duplication can be an initial step in gene amplification.Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunitiesGene amplification accompanied by the loss of a chromosome containing the native allele and the appearance of the amplified DNA at a new chromosomal location.De novo chromosome formation in rodent cells.Enhanced flexibility and aphidicolin-induced DNA breaks near mammalian replication origins: implications for replicon mapping and chromosome fragility.A cruciform-dumbbell model for inverted dimer formation mediated by inverted repeatsAn intramolecular recombination mechanism for the formation of the rRNA gene palindrome of Tetrahymena thermophila.Long palindromes formed in Streptomyces by nonrecombinational intra-strand annealing.Nucleotide sequence of both reciprocal translocation junction regions in a patient with Ph positive acute lymphoblastic leukaemia, with a breakpoint within the first intron of the BCR gene.Amplified inverted duplications within and adjacent to heterologous selectable DNA.Large inverted duplications in amplified DNA of mammalian cells form hairpins in vitro upon DNA extraction but not in vivo.Gene targeting with retroviral vectors: recombination by gene conversion into regions of nonhomology.Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently recombined DNA.Structure of a palindromic amplicon junction implicates microhomology-mediated end joining as a mechanism of sister chromatid fusion during gene amplification.Direct and inverted DNA repeats associated with P-glycoprotein gene amplification in drug resistant Leishmania.Transposition of human immunoglobulin V kappa genes within the same chromosome and the mechanism of their amplification.
P2860
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P2860
The multicopy appearance of a large inverted duplication and the sequence at the inversion joint suggest a new model for gene amplification.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
The multicopy appearance of a ...... model for gene amplification.
@en
type
label
The multicopy appearance of a ...... model for gene amplification.
@en
prefLabel
The multicopy appearance of a ...... model for gene amplification.
@en
P2093
P2860
P1433
P1476
The multicopy appearance of a ...... model for gene amplification.
@en
P2093
Debatisse M
de Saint Vincent BR
P2860
P304
P407
P577
1988-02-01T00:00:00Z