A Kaposi's sarcoma-associated herpesvirus-encoded cytokine homolog (vIL-6) activates signaling through the shared gp130 receptor subunit.
about
Detection of direct binding of human herpesvirus 8-encoded interleukin-6 (vIL-6) to both gp130 and IL-6 receptor (IL-6R) and identification of amino acid residues of vIL-6 important for IL-6R-dependent and -independent signalingStimulation of c-Myc transcriptional activity by vIRF-3 of Kaposi sarcoma-associated herpesvirusThe viral etiology of AIDS-associated malignanciesKSHV-Mediated Angiogenesis in Tumor ProgressionRegulation of the Host Antiviral State by Intercellular CommunicationsKSHV: pathways to tumorigenesis and persistent infectionBlockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirusKaposi's Sarcoma–Associated Herpesvirus Immunoevasion and Tumorigenesis: Two Sides of the Same Coin?Identification and analysis of the K5 gene of Kaposi's sarcoma-associated herpesvirus.Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage displayK13 blocks KSHV lytic replication and deregulates vIL6 and hIL6 expression: a model of lytic replication induced clonal selection in viral oncogenesis.Molecular biology of KSHV in relation to AIDS-associated oncogenesis.V3 recombinants indicate a central role for CCR5 as a coreceptor in tissue infection by human immunodeficiency virus type 1.KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine.Human herpesvirus 8-encoded cytokines.Human herpesvirus 8 interleukin-6 (vIL-6) signals through gp130 but has structural and receptor-binding properties distinct from those of human IL-6.Spectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseasesThe role of cytokines in the pathogenesis and management of AIDS-related lymphomas.Evolutionary aspects of oncogenic herpesvirusesExploitation of the complement system by oncogenic Kaposi's sarcoma-associated herpesvirus for cell survival and persistent infectionIdentification of amino acid residues of gp130 signal transducer and gp80 alpha receptor subunit that are involved in ligand binding and signaling by human herpesvirus 8-encoded interleukin-6.Human tumor-associated viruses and new insights into the molecular mechanisms of cancer.Immune evasion by Kaposi's sarcoma-associated herpesvirus.Analysis of 4.3 kilobases of divergent locus B of macaque retroperitoneal fibromatosis-associated herpesvirus reveals a close similarity in gene sequence and genome organization to Kaposi's sarcoma-associated herpesvirusTranscriptional regulation of the interleukin-6 gene of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus).Molecular biology of KSHV lytic reactivation.Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) epidemiology and pathogenesis.Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulenceThe KSHV viral interleukin-6 is not essential for latency or lytic replication in BJAB cells.ORF18 is a transfactor that is essential for late gene transcription of a gammaherpesvirus.Structural requirements for gp80 independence of human herpesvirus 8 interleukin-6 (vIL-6) and evidence for gp80 stabilization of gp130 signaling complexes induced by vIL-6.Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesisKaposi sarcoma-associated herpesvirus (KSHV): molecular biology and oncogenesisThe role of Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 regulator of transcription activation (RTA) in control of gene expression.Oncovirus Kaposi sarcoma herpesvirus (KSHV) represses tumor suppressor PDLIM2 to persistently activate nuclear factor κB (NF-κB) and STAT3 transcription factors for tumorigenesis and tumor maintenance.HIV-associated multicentric Castleman diseaseViral interleukin-6: role in Kaposi's sarcoma-associated herpesvirus: associated malignancies.Human herpesvirus 8 viral interleukin-6 interacts with splice variant 2 of vitamin K epoxide reductase complex subunit 1.Cytokine homologs of human gammaherpesviruses.Expression of a virus-derived cytokine, KSHV vIL-6, in HIV-seronegative Castleman's disease.
P2860
Q24290902-5F20E895-0C35-4B53-9DD6-1DCE20CEBFA7Q24338664-ED18EED7-8457-4DFD-9124-7DE264071033Q24685892-40FBBCD6-CF9E-4B33-BF88-183421ABC872Q26742030-24BF88C7-BA52-4A3F-9C96-F9604A589D9BQ26795744-32A3C4E2-F8FC-4686-8201-40DA3F8EE386Q27026000-AF14CDD7-C37D-46F2-A52C-3B3F77404C52Q27486045-0ECBCFB9-56C6-4B75-8B7C-13BF35161023Q29394711-F2443213-8BCD-4689-A8C6-BB7C03A72389Q30840864-B46ACD3E-4AB6-47F6-80D1-AD47E9601C7FQ33254113-688B221D-6234-46B1-8883-062D786BCC15Q33303677-72178F1B-97D9-466B-9EFE-D4579AEC6AEDQ33560572-CB52BE29-9784-4200-84D1-26A7F079B1F6Q33653627-49963A5F-3CF9-43D5-8DE1-58620043DBC3Q33761091-453127F2-063E-484C-8513-6C2F7D024D25Q33813244-72B5DD43-D161-4440-A26D-08C9498F1A76Q33819690-CCB7DC9F-DD77-4F86-BF7F-3DA51481F6C1Q33906970-2CCAF484-974F-49F8-8818-C316EDC29012Q34011536-1D226266-1FB2-4B7F-B3DD-1CD32532F5F2Q34089478-A0C52603-D20E-4ECE-BB3F-CC8E5FAAC954Q34257818-EEC3CA41-A01A-4D06-A24E-16D7CD04169AQ34365452-0F9A193B-80E4-45FB-918F-89F41698FBCBQ34614394-EC408BB0-D653-4FC7-9DC0-BE0B75EAACB9Q34795543-8B16000C-04B7-49B9-A3E5-C52E1C522B4EQ34976331-9D9DE1B3-7EBE-44BE-88C5-DAE427759077Q35000927-D6651128-7C15-4574-AB84-5F53CF014CF4Q35014918-A3168470-B1DF-4DFE-B8D4-985B3F6FADF0Q35026060-B1471642-9FF0-4F67-85AF-F6C4EA02E183Q35035005-7619072A-ACFD-4BD4-BF70-9EB48F9C90C8Q35071118-A5BE219C-7944-43A1-9DA6-1B6340EF500CQ35101383-DF3B6AD7-33F3-4B78-BBFD-28028ADA7584Q35101444-722319D5-3142-489F-8F30-C27B145C85B7Q35124404-03951E57-9269-432E-91BD-6C75AC565262Q35127940-1E223471-A215-482E-B942-CE82BB997950Q35196615-7C08BA60-6439-4F5D-8D79-461B877E03F4Q35199327-0160A4D2-7A48-40B4-BFDE-241B25AC8582Q35226470-C006871D-FDA4-4B2C-95EB-9F7DFE2069F3Q35550033-E32FD3D4-D85B-4A98-9CA4-2382A3753C32Q35689626-D1B1C0FA-540A-43B9-AB3A-FEAB055091FDQ35743839-C164E065-7739-4702-A21C-5B30C633A981Q35764989-7498DA5D-97B6-4E9B-A78A-1787540E1877
P2860
A Kaposi's sarcoma-associated herpesvirus-encoded cytokine homolog (vIL-6) activates signaling through the shared gp130 receptor subunit.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
A Kaposi's sarcoma-associated ...... shared gp130 receptor subunit.
@en
type
label
A Kaposi's sarcoma-associated ...... shared gp130 receptor subunit.
@en
prefLabel
A Kaposi's sarcoma-associated ...... shared gp130 receptor subunit.
@en
P2093
P2860
P356
P1476
A Kaposi's sarcoma-associated ...... shared gp130 receptor subunit.
@en
P2093
P2860
P304
19625-19631
P356
10.1074/JBC.272.31.19625
P407
P577
1997-08-01T00:00:00Z