Multiple di-leucines in the ATP7A copper transporter are required for retrograde trafficking to the trans-Golgi network.

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Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease

P2860

Q42189067-575EBEB6-C7E8-4F86-82AF-2214235A8546

P2860

Multiple di-leucines in the ATP7A copper transporter are required for retrograde trafficking to the trans-Golgi network.

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http://www.wikidata.org/entity/Q41105245

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2016 nî lūn-bûn

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2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Multiple di-leucines in the AT ...... ng to the trans-Golgi network.

@en

type

Item

label

Multiple di-leucines in the AT ...... ng to the trans-Golgi network.

@en

prefLabel

Multiple di-leucines in the AT ...... ng to the trans-Golgi network.

@en

P1476

Multiple di-leucines in the AT ...... ng to the trans-Golgi network.

@en

P2093

Michael J Petris

http://www.w3.org/2001/XMLSchema#string

Sha Zhu

http://www.w3.org/2001/XMLSchema#string

Victoria L Hodgkinson

http://www.w3.org/2001/XMLSchema#string

Vinit Shanbhag

http://www.w3.org/2001/XMLSchema#string

P2860

A C-terminal di-leucine is required for localization of the Menkes protein in the trans-Golgi network

The Menkes copper transporter is required for the activation of tyrosinase

Biochemical characterization and intracellular localization of the Menkes disease protein

Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking

Diverse mutations in patients with Menkes disease often lead to exon skipping

A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex

A novel frameshift mutation in exon 23 of ATP7A (MNK) results in occipital horn syndrome and not in Menkes disease

Conditional knockout of the Menkes disease copper transporter demonstrates its critical role in embryogenesis

The Menkes protein (ATP7A; MNK) cycles via the plasma membrane both in basal and elevated extracellular copper using a C-terminal di-leucine endocytic signal

P304

993-1001

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1039/C6MT00093B

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2016-06-23T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

27337370

http://www.w3.org/2001/XMLSchema#string

P932

5025395

http://www.w3.org/2001/XMLSchema#string

Multiple di-leucines in the ATP7A copper transporter are required for retrograde trafficking to the trans-Golgi network.

about

P2860

P2860

Multiple di-leucines in the ATP7A copper transporter are required for retrograde trafficking to the trans-Golgi network.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932