Karyotypic analysis of gastric carcinoma cell lines carrying an amplified c-met oncogene.
about
Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutationsThe Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variantsExome sequencing reveals comprehensive genomic alterations across eight cancer cell linesActivation of HER family members in gastric carcinoma cells mediates resistance to MET inhibition.Analysis of MET mRNA expression in gastric cancers using RNA in situ hybridization assay: its clinical implication and comparison with immunohistochemistry and silver in situ hybridization.RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.High MET expression is an adverse prognostic factor in patients with triple-negative breast cancerDiscovery of fully human anti-MET monoclonal antibodies with antitumor activity against colon cancer tumor models in vivo.EV20, a Novel Anti-ErbB-3 Humanized Antibody, Promotes ErbB-3 Down-Regulation and Inhibits Tumor Growth In Vivo.Erythropoietin receptor transcription is neither elevated nor predictive of surface expression in human tumour cells.Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil.Excessive MET signaling causes acquired resistance and addiction to MET inhibitors in the MKN45 gastric cancer cell line.An ErbB-3 antibody, MP-RM-1, inhibits tumor growth by blocking ligand-dependent and independent activation of ErbB-3/Akt signaling.Recombinant immunotoxin anti-c-Met/PE38KDEL inhibits proliferation and promotes apoptosis of gastric cancer cellsA preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.Development of a cell-based assay for measurement of c-Met phosphorylation using AlphaScreen technology and high-content imaging analysis.Expression of RUNX3 protein in human gastric mucosa, intestinal metaplasia and carcinoma.BE-23372M, a novel and specific inhibitor for epidermal growth factor receptor kinase.Unexpected renal toxicity associated with SGX523, a small molecule inhibitor of MET.Tissue microarray analysis of multiple gene expression in intestinal metaplasia, dysplasia and carcinoma of the stomach.Silencing the MET oncogene leads to regression of experimental tumors and metastases
P2860
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P2860
Karyotypic analysis of gastric carcinoma cell lines carrying an amplified c-met oncogene.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Karyotypic analysis of gastric carcinoma cell lines carrying an amplified c-met oncogene.
@en
type
label
Karyotypic analysis of gastric carcinoma cell lines carrying an amplified c-met oncogene.
@en
prefLabel
Karyotypic analysis of gastric carcinoma cell lines carrying an amplified c-met oncogene.
@en
P2093
P50
P1476
Karyotypic analysis of gastric carcinoma cell lines carrying an amplified c-met oncogene
@en
P2093
C Ponzetto
G Rege-Cambrin
P Scaravaglio
P304
P356
10.1016/0165-4608(92)90350-H
P577
1992-12-01T00:00:00Z