Expression of small extracellular chondroitin/dermatan sulfate proteoglycans is differentially regulated in human endothelial cells.
about
Endocan is a novel chondroitin sulfate/dermatan sulfate proteoglycan that promotes hepatocyte growth factor/scatter factor mitogenic activityGlycoconjugates and related molecules in human vascular endothelial cellsDecorin is produced by capillary endothelial cells in inflammation-associated angiogenesis.Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.Decreased body fat, elevated plasma transforming growth factor-β levels, and impaired BMP4-like signaling in biglycan-deficient mice.Characterization of released polypeptides during an interferon-γ-dependent antibacterial response in airway epithelial cells.ADAMTS-4 and biglycan are expressed at high levels and co-localize to podosomes during endothelial cell tubulogenesis in vitro.Biglycan gene expression in the human leiomyosarcoma cell line SK-UT-1. Basal and protein kinase A-induced transcription involves binding of Sp1-like/Sp3 proteins in the proximal promoter region.Regulation of biglycan gene expression by transforming growth factor-beta requires MKK6-p38 mitogen-activated protein Kinase signaling downstream of Smad signaling.A finite dissipative theory of temporary interfibrillar bridges in the extracellular matrix of ligaments and tendons.Decorin-mediated signal transduction in endothelial cells. Involvement of Akt/protein kinase B in up-regulation of p21(WAF1/CIP1) but not p27(KIP1).Cell adhesion and migration properties of beta 2-integrin negative polymorphonuclear granulocytes on defined extracellular matrix molecules. Relevance for leukocyte extravasation.Matrix metalloproteinase expression by endothelial cells in collagen lattices changes during co-culture with fibroblasts and upon induction of decorin expression.Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells.Decorin is a secreted protein associated with obesity and type 2 diabetes.Benign hyperplasia of the human prostate is associated with tissue enrichment in chondroitin sulphate of wide size distribution.Biglycan expression correlates with aggressiveness and poor prognosis of gastric cancer.
P2860
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P2860
Expression of small extracellular chondroitin/dermatan sulfate proteoglycans is differentially regulated in human endothelial cells.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Expression of small extracellu ...... ed in human endothelial cells.
@en
type
label
Expression of small extracellu ...... ed in human endothelial cells.
@en
prefLabel
Expression of small extracellu ...... ed in human endothelial cells.
@en
P2093
P2860
P356
P1476
Expression of small extracellu ...... ed in human endothelial cells.
@en
P2093
Jalkanen M
Jortikka M
Järveläinen H
Kainulainen V
Moisander S
Nelimarkka L
Schönherr E
P2860
P304
12730-12737
P356
10.1074/JBC.272.19.12730
P407
P577
1997-05-01T00:00:00Z