Increased biological activity of protein Kinase C gamma is not required in Spinocerebellar ataxia 14.

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Increased biological activity of protein Kinase C gamma is not required in Spinocerebellar ataxia 14.

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年论文

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Increased biological activity ...... in Spinocerebellar ataxia 14.

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Increased biological activity ...... in Spinocerebellar ataxia 14.

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Increased biological activity ...... in Spinocerebellar ataxia 14.

@en

P1476

Increased biological activity ...... in Spinocerebellar ataxia 14.

@en

P2093

Etsuko Shimobayashi

http://www.w3.org/2001/XMLSchema#string

Josef P Kapfhammer

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P2860

Protein kinase C and lipid signaling for sustained cellular responses

Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice

Protein kinase C gamma (PKC gamma): function of neuron specific isotype.

An efficient method for the long-term and specific expression of exogenous cDNAs in cultured Purkinje neurons.

The analysis of purkinje cell dendritic morphology in organotypic slice cultures.

Protein kinase C gamma, a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin.

Activation of mutant protein kinase Cgamma leads to aberrant sequestration and impairment of its cellular function.

Organotypic slice cultures: a technique has come of age.

PKC gamma mutations in spinocerebellar ataxia type 14 affect C1 domain accessibility and kinase activity leading to aberrant MAPK signaling.

SCA14 mutation V138E leads to partly unfolded PKCγ associated with an exposed C-terminus, altered kinetics, phosphorylation and enhanced insolubilization.

P2888

s13041-017-0313-z

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scholarly article

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10.1186/S13041-017-0313-Z

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Josef P Kapfhammer

Etsuko Shimobayashi

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2017-07-24T00:00:00Z

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1090885793

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28738819

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5525338

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