Differential effect of acetyltransferase expression on the genotoxicity of heterocyclic amines in CHO cells.
about
Genetically modified Chinese hamster ovary cells for investigating sulfotransferase-mediated cytotoxicity and mutation by 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridineMetabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic aminesEffect of rapid human N-acetyltransferase 2 haplotype on DNA damage and mutagenesis induced by 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MeIQx).Human exposure to heterocyclic amine food mutagens/carcinogens: relevance to breast cancer.Diallyl sulfide inhibits PhIP-induced cell death via the inhibition of DNA strand breaks in normal human breast epithelial cells.NATb/NAT1*4 promotes greater arylamine N-acetyltransferase 1 mediated DNA adducts and mutations than NATa/NAT1*4 following exposure to 4-aminobiphenylMass Spectrometric Characterization of Human Serum Albumin Adducts Formed with N-Oxidized Metabolites of 2-Amino-1-methylphenylimidazo[4,5-b]pyridine in Human Plasma and Hepatocytes2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline-induced DNA adduct formation and mutagenesis in DNA repair-deficient Chinese hamster ovary cells expressing human cytochrome P4501A1 and rapid or slow acetylator N-acetyltransferase 2The impact of NAT2 acetylator genotype on mutagenesis and DNA adducts from 2-amino-9H-pyrido[2,3-b]indole.Role of human CYP1A1 and NAT2 in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mutagenicity and DNA adducts.Heterocyclic aromatic amines induce DNA strand breaks and cell transformation.Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay.2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine-induced DNA adducts and genotoxicity in chinese hamster ovary (CHO) cells expressing human CYP1A2 and rapid or slow acetylator N-acetyltransferase 2.
P2860
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P2860
Differential effect of acetyltransferase expression on the genotoxicity of heterocyclic amines in CHO cells.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Differential effect of acetylt ...... erocyclic amines in CHO cells.
@en
type
label
Differential effect of acetylt ...... erocyclic amines in CHO cells.
@en
prefLabel
Differential effect of acetylt ...... erocyclic amines in CHO cells.
@en
P2093
P1433
P1476
Differential effect of acetylt ...... erocyclic amines in CHO cells.
@en
P2093
J D Tucker
J S Felton
K J Sorensen
L H Thompson
P304
P356
10.1016/S0165-1218(97)00005-0
P407
P577
1997-04-01T00:00:00Z