Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase.
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The essential role of profilin in the assembly of actin for microspike formation.Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinasePhosphorylation of a novel myosin binding subunit of protein phosphatase 1 reveals a conserved mechanism in the regulation of actin cytoskeletonRho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarityKIF14 negatively regulates Rap1a-Radil signaling during breast cancer progressionNuclear Rho kinase, ROCK2, targets p300 acetyltransferaseRACK1 promotes breast carcinoma migration/metastasis via activation of the RhoA/Rho kinase pathwayMyotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganizationCaspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling regionHyaluronan-CD44 interaction promotes c-Src-mediated twist signaling, microRNA-10b expression, and RhoA/RhoC up-regulation, leading to Rho-kinase-associated cytoskeleton activation and breast tumor cell invasionCofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formationThe GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathwayPhysical and functional interactions of Galphaq with Rho and its exchange factorsCofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2Differential regulation of pulmonary endothelial monolayer integrity by varying degrees of cyclic stretchRho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail associationFocal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanismIQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilamentsPhosphorylation of adducin by Rho-kinase plays a crucial role in cell motilityRoles of Rho-associated kinase in cytokinesis; mutations in Rho-associated kinase phosphorylation sites impair cytokinetic segregation of glial filamentsAdducin is an in vivo substrate for protein kinase C: phosphorylation in the MARCKS-related domain inhibits activity in promoting spectrin-actin complexes and occurs in many cells, including dendritic spines of neuronsRho, ROCK and actomyosin contractility in metastasis as drug targetsMechanical signaling in reproductive tissues: mechanisms and importanceROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity.Cooperative anti-invasive effect of Cdc42/Rac1 activation and ROCK inhibition in SW620 colorectal cancer cells with elevated blebbing activityThe RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin ContractilityProtective effects of the mTOR inhibitor everolimus on cytoskeletal injury in human podocytes are mediated by RhoA signalingPlasticity in the macromolecular-scale causal networks of cell migrationbFGF regulates PI3-kinase-Rac1-JNK pathway and promotes fibroblast migration in wound healingParallel coiled-coil association of the RhoA-binding domain in Rho-kinaseMechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structureCrystal Structure of a Coiled-Coil Domain from Human ROCK ICrystal structure of human RhoA in a dominantly active form complexed with a GTP analogueFunctions of a rho-specific guanine nucleotide exchange factor in neurite retraction. Possible role of a proline-rich motif of KIAA0380 in localizationPhosphorylation of collapsin response mediator protein-2 by Rho-kinase. Evidence for two separate signaling pathways for growth cone collapseThe RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organizationAnalysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7A molecular ruler regulates cytoskeletal remodelling by the Rho kinasesERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migrationIdentification of an interaction between the m-band protein skelemin and beta-integrin subunits. Colocalization of a skelemin-like protein with beta1- and beta3-integrins in non-muscle cells
P2860
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P2860
Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase.
@en
type
label
Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase.
@en
prefLabel
Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase.
@en
P2093
P1433
P1476
Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase.
@en
P2093
Kaibuchi K
Matsuura Y
Nakamura N
P304
P356
10.1126/SCIENCE.275.5304.1308
P407
P577
1997-02-01T00:00:00Z