Assembly of immunoglobulin light chains as a prerequisite for secretion. A model for oligomerization-dependent subunit folding.
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Disulfide bonds in ER protein folding and homeostasispERp1 is significantly up-regulated during plasma cell differentiation and contributes to the oxidative folding of immunoglobulinBinding of free immunoglobulin light chains to VpreB3 inhibits their maturation and secretion in chicken B cells.The role of cis dimerization of signal regulatory protein alpha (SIRPalpha) in binding to CD47An internal ribosome entry site (IRES) mutant library for tuning expression level of multiple genes in mammalian cells.The variable domain of nonassembled Ig light chains determines both their half-life and binding to the chaperone BiP.Versatility of the endoplasmic reticulum protein folding factory.The VCP/p97 and YOD1 Proteins Have Different Substrate-dependent Activities in Endoplasmic Reticulum-associated Degradation (ERAD)Endoplasmic reticulum chaperones are involved in the morphogenesis of rotavirus infectious particles.Dominant protein interactions that influence the pathogenesis of conformational diseases.Alternative-splicing-based bicistronic vectors for ratio-controlled protein expression and application to recombinant antibody production.How antibodies foldCysteines in CH1 underlie retention of unassembled Ig heavy chains.BiP and immunoglobulin light chain cooperate to control the folding of heavy chain and ensure the fidelity of immunoglobulin assembly.CTLA4Fcε, a novel soluble fusion protein that binds B7 molecules and the IgE receptors, and reduces human in vitro soluble CD23 production and lymphocyte proliferation.Free light chain content in culture media reflects recombinant monoclonal antibody productivity and quality.Inhibition of secretion of interleukin (IL)-12/IL-23 family cytokines by 4-trifluoromethyl-celecoxib is coupled to degradation via the endoplasmic reticulum stress protein HERP.The C-terminal extension of a hybrid immunoglobulin A/G heavy chain is responsible for its Golgi-mediated sorting to the vacuoleCreation of a bi-directional protein transduction system for suppression of HIV-1 expression by p27SJ.Recovering antibody secretion using a hapten ligand as a chemical chaperone.IgG light chain-independent secretion of heavy chain dimers: consequence for therapeutic antibody production and design.Development of a single-replicon miniBYV vector for co-expression of heterologous proteins.Alternative pathways of disulfide bond formation yield secretion-competent, stable and functional immunoglobulins.Impact of gene vector design on the control of recombinant monoclonal antibody production by Chinese hamster ovary cells.Folding and self-assembly do not prevent ER retention and proteasomal degradation of asialoglycoprotein receptor H2a.Assembly-induced folding regulates interleukin 12 biogenesis and secretion.Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function.Development of a novel affinity chromatography resin for platform purification of lambda fabs.Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells.Predicting the expression of recombinant monoclonal antibodies in Chinese hamster ovary cells based on sequence features of the CDR3 domain.Effect of VH-VL Families in Pertuzumab and Trastuzumab Recombinant Production, Her2 and FcγIIA Binding.
P2860
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P2860
Assembly of immunoglobulin light chains as a prerequisite for secretion. A model for oligomerization-dependent subunit folding.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Assembly of immunoglobulin lig ...... ion-dependent subunit folding.
@en
type
label
Assembly of immunoglobulin lig ...... ion-dependent subunit folding.
@en
prefLabel
Assembly of immunoglobulin lig ...... ion-dependent subunit folding.
@en
P2093
P2860
P356
P1476
Assembly of immunoglobulin lig ...... ion-dependent subunit folding.
@en
P2093
P2860
P304
P356
10.1074/JBC.272.5.3117
P407
P577
1997-01-01T00:00:00Z