Evidence for the involvement of cGMP and protein kinase G in nitric oxide-induced apoptosis in the pancreatic B-cell line, HIT-T15.
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Effects of tyrosine kinase inhibitors on cell death induced by sodium fluoride and pertussis toxin in the pancreatic beta-cell line, RINm5FEndogenous endothelial cell nitric-oxide synthase modulates apoptosis in cultured breast cancer cells and is transcriptionally regulated by p53A dose-ranging study of the pharmacokinetics and pharmacodynamics of the selective apoptotic antineoplastic drug (SAAND), OSI-461, in patients with advanced cancer, in the fasted and fed stateNitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway.Inhibition of phosphodiestrase 9 induces cGMP accumulation and apoptosis in human breast cancer cell lines, MCF-7 and MDA-MB-468.Stabilization of cGMP-dependent protein kinase G (PKG) expression in vascular smooth muscle cells: contribution of 3'UTR of its mRNAProstacyclin prevents nitric oxide-induced megakaryocyte apoptosisInducible nitric oxide synthase is crucial for plasma cell survival.Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer.Activation of guanylate cyclase C signaling pathway protects intestinal epithelial cells from acute radiation-induced apoptosis.Global metabolomics reveals potential urinary biomarkers of esophageal squamous cell carcinoma for diagnosis and stagingNitric oxide released from JS-K induces cell death by mitotic catastrophe as part of necrosis in glioblastoma multiforme.cGMP-dependent protein kinase: linking foraging to energy homeostasis.Pancreatic-β-cell survival and proliferation are promoted by protein kinase G type Iα and downstream regulation of AKT/FOXO1.Induction of apoptosis by type Iβ protein kinase G in the human breast cancer cell lines MCF-7 and MDA-MB-468.Cyclic GMP induced apoptosis via protein kinase G in oestrogen receptor-positive and -negative breast cancer cell lines.Proliferation of macrophages due to the inhibition of inducible nitric oxide synthesis by oxidized low-density lipoproteins.Involvement of the cGMP signalling pathway in the regulation of viability in insulin-secreting BRIN-BD11 cells.High glucose potentiates palmitate-induced NO-mediated cytotoxicity through generation of superoxide in clonal beta-cell HIT-T15.Phosphorylation of NF-kappaB proteins by cyclic GMP-dependent kinase. A noncanonical pathway to NF-kappaB activation.S-nitrosation controls gating and conductance of the alpha 1 subunit of class C L-type Ca(2+) channels.NO induces a cGMP-independent release of cytochrome c from mitochondria which precedes caspase 3 activation in insulin producing RINm5F cells.The involvement of protein kinase C in nitric oxide-induced damage to rat isolated colonic mucosal cells.Transcriptional activation of the haem oxygenase-1 gene by cGMP via a cAMP response element/activator protein-1 element in primary cultures of rat hepatocytes.Evaluation of islet heme oxygenase-CO and nitric oxide synthase-NO pathways during acute endotoxemia.NO upregulation of a cyclic nucleotide-gated channel contributes to calcium elevation in endothelial cells.B-type natriuretic peptide limits infarct size in rat isolated hearts via KATP channel opening.Mono-unsaturated fatty acids protect against beta-cell apoptosis induced by saturated fatty acids, serum withdrawal or cytokine exposure.Nitric oxide donors, nitrosothiols and mitochondrial respiration inhibitors induce caspase activation by different mechanisms.Chronic blockade of NO synthase paradoxically increases islet NO production and modulates islet hormone release.Inducible nitric oxide synthase is a major intermediate in signaling pathways for the survival of plasma cells.Expression of cGMP-dependent protein kinase, PKGIα, PKGIβ, and PKGII in malignant and benign breast tumors.
P2860
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P2860
Evidence for the involvement of cGMP and protein kinase G in nitric oxide-induced apoptosis in the pancreatic B-cell line, HIT-T15.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Evidence for the involvement o ...... ncreatic B-cell line, HIT-T15.
@en
type
label
Evidence for the involvement o ...... ncreatic B-cell line, HIT-T15.
@en
prefLabel
Evidence for the involvement o ...... ncreatic B-cell line, HIT-T15.
@en
P2093
P1433
P1476
Evidence for the involvement o ...... ncreatic B-cell line, HIT-T15.
@en
P2093
Scarpello JH
Williams GT
P304
P356
10.1016/S0014-5793(96)01392-0
P407
P577
1997-01-01T00:00:00Z