Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia.
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Functional Diversification of Motor Neuron-specific Isl1 Enhancers during EvolutionAutomatic zebrafish heartbeat detection and analysis for zebrafish embryos.Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish.Shox2 is required for the proper development of the facial motor nucleus and the establishment of the facial nervesPotential effects of intrinsic heart pacemaker cell mechanisms on dysrhythmic cardiac action potential firingRNA sequencing of mouse sinoatrial node reveals an upstream regulatory role for Islet-1 in cardiac pacemaker cells.The sinus venosus myocardium contributes to the atrioventricular canal: potential role during atrioventricular node development?A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node.Transcription factor ISL1 is essential for pacemaker development and function.Coding and non-coding variants in the SHOX2 gene in patients with early-onset atrial fibrillation.Morpho-functional characterization of the systemic venous pole of the reptile heart.The impact of inflammatory lipid mediators on colon cancer-initiating cells.Development of the cardiac pacemakerTbx18 and the generation of a biological pacemaker. Are we there yet?Development and Function of the Cardiac Conduction System in Health and Disease.On the Evolution of the Cardiac Pacemaker.nkx genes establish SHF cardiomyocyte progenitors at the arterial pole and pattern the venous pole through Isl1 repression.Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules.RHOA-ROCK signalling is necessary for lateralization and differentiation of the developing sinoatrial node.No effect of thymosin beta-4 on the expression of the transcription factor Islet-1 in the adult murine heart.A loss-of-function mutation underlying familial atrial fibrillation
P2860
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P2860
Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Islet1 is a direct transcripti ...... he Shox2-mediated bradycardia.
@en
type
label
Islet1 is a direct transcripti ...... he Shox2-mediated bradycardia.
@en
prefLabel
Islet1 is a direct transcripti ...... he Shox2-mediated bradycardia.
@en
P2093
P2860
P1476
Islet1 is a direct transcripti ...... he Shox2-mediated bradycardia.
@en
P2093
Anne Glaser
Claire Bacon
Gudrun Rappold
Herbert Steinbeisser
Ina M Berger
Sandra Hoffmann
Steffen Just
Wolfgang Rottbauer
P2860
P2888
P356
10.1007/S00395-013-0339-Z
P577
2013-03-01T00:00:00Z