Diverse roles of STING-dependent signaling on the development of cancer
about
STING: infection, inflammation and cancerMolecular Pathways: Targeting the Stimulator of Interferon Genes (STING) in the Immunotherapy of CancerCell Free DNA of Tumor Origin Induces a 'Metastatic' Expression Profile in HT-29 Cancer Cell Line.The host STING pathway at the interface of cancer and immunityOncolytic immunotherapy: The new clinical outbreak.Mitochondria and the hallmarks of cancer.STING Requires the Adaptor TRIF to Trigger Innate Immune Responses to Microbial InfectionKeratin 8-deletion induced colitis predisposes to murine colorectal cancer enforced by the inflammasome and IL-22 pathway.The role of cGAS in innate immunity and beyond.The expanding regulatory network of STING-mediated signaling.Innate immune mediators in cancer: between defense and resistance.Nucleic acid sensing and innate immunity: signaling pathways controlling viral pathogenesis and autoimmunity.Innate immune signaling and regulation in cancer immunotherapy.Rationale for stimulator of interferon genes-targeted cancer immunotherapy.Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis.STING-mediated DNA sensing in cancer immunotherapy.STING signalling: an emerging common pathway in autoimmunity and cancer.Mechanisms regulating immune surveillance of cellular stress in cancer.Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation.An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway.Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis.Role of Type I and II Interferons in Colorectal Cancer and Melanoma.cGAS/STING Pathway in Cancer: Jekyll and Hyde Story of Cancer Immune Response.Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation.STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis.Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway.Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1β.Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production.The cytosolic sensor STING is required for intestinal homeostasis and control of inflammation.
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Diverse roles of STING-dependent signaling on the development of cancer
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Diverse roles of STING-dependent signaling on the development of cancer
@en
type
label
Diverse roles of STING-dependent signaling on the development of cancer
@en
prefLabel
Diverse roles of STING-dependent signaling on the development of cancer
@en
P2093
P2860
P356
P1433
P1476
Diverse roles of STING-dependent signaling on the development of cancer
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2014.457
P407
P577
2015-02-02T00:00:00Z
P6179
1026638841