Bax homodimerization is not required for Bax to accelerate chemotherapy-induced cell death.
about
PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cellsEnforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosisEffects and mechanisms of emodin on cell death in human lung squamous cell carcinomaA splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitroThe N-terminus and alpha-5, alpha-6 helices of the pro-apoptotic protein Bax, modulate functional interactions with the anti-apoptotic protein Bcl-xL.Controlling the mitochondrial gatekeeper for effective chemotherapy.Driving p53 response to Bax activation greatly enhances sensitivity to taxol by inducing massive apoptosis.Bcl-2 is a monomeric protein: prevention of homodimerization by structural constraints.Bax-induced apoptotic cell death.Abnormal intracellular localization of Bax with a normal membrane anchor domain in human lung cancer cell lines.Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing.Control of Bax homodimerization by its carboxyl terminus.The BH3 domain of Bax is sufficient for interaction of Bax with itself and with other family members and it is required for induction of apoptosis.Deciphering the apoptotic pathway: all roads lead to death.tBid elicits a conformational alteration in membrane-bound Bcl-2 such that it inhibits Bax pore formationHeterodimerization-independent functions of cell death regulatory proteins Bax and Bcl-2 in yeast and mammalian cells.Retroviral BAX gene transfer fails to sensitize malignant glioma cells to CD95L-induced apoptosis and cancer chemotherapy.Caspase-3 activation is not responsible for vinblastine-induced Bcl-2 phosphorylation and G2/M arrest in human small cell lung carcinoma Ms-1 cells.
P2860
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P2860
Bax homodimerization is not required for Bax to accelerate chemotherapy-induced cell death.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Bax homodimerization is not re ...... emotherapy-induced cell death.
@en
type
label
Bax homodimerization is not re ...... emotherapy-induced cell death.
@en
prefLabel
Bax homodimerization is not re ...... emotherapy-induced cell death.
@en
P2093
P2860
P356
P1476
Bax homodimerization is not re ...... emotherapy-induced cell death.
@en
P2093
P2860
P304
32073-32077
P356
10.1074/JBC.271.50.32073
P407
P577
1996-12-01T00:00:00Z