The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells.
about
Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) miceThe PD-1 pathway in tolerance and autoimmunityBreaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression.Inducing and Administering Tregs to Treat Human DiseasePromises and paradoxes of regulatory T cells in inflammatory bowel diseaseHomeostasis and function of regulatory T cells (Tregs) in vivo: lessons from TCR-transgenic TregsConcise Review: Cell-Based Therapies and Other Non-Traditional Approaches for Type 1 DiabetesAntigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune DiseasesGenetics, pathogenesis and clinical interventions in type 1 diabetesRegulatory T Cells Control Th2-Dominant Murine Autoimmune GastritisDefects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjectsApoptosis of purified CD4+ T cell subsets is dominated by cytokine deprivation and absence of other cells in new onset diabetic NOD mice.Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis.Prediction and pathogenesis in type 1 diabetes.Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance.Immune tolerance induction by integrating innate and adaptive immune regulators.Effector and naturally occurring regulatory T cells display no abnormalities in activation induced cell death in NOD miceDendritic cell-targeted pancreatic beta-cell antigen leads to conversion of self-reactive CD4(+) T cells into regulatory T cells and promotes immunotolerance in NOD mice.Human regulatory T cells in autoimmune diseasesFoxp3+ Treg expanded from patients with established diabetes reduce Helios expression while retaining normal function compared to healthy individuals.Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseasesCutting edge: Genetic variation in TLR1 is associated with Pam3CSK4-induced effector T cell resistance to regulatory T cell suppression.Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes.Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes.Challenges in the pursuit of immune tolerance.A cluster of coregulated genes determines TGF-beta-induced regulatory T-cell (Treg) dysfunction in NOD miceTemporal intra-individual variation of immunological biomarkers in type 1 diabetes patients: implications for future use in cross-sectional assessmentType-specific human papillomavirus detection in cervical smears in Romania.Uncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes.CD4+FOXP3+ T regulatory cells in human autoimmunity: more than a numbers gameGanglioside GM1 deficiency in effector T cells from NOD mice induces resistance to regulatory T-cell suppressionThe dual effects of B cell depletion on antigen-specific T cells in BDC2.5NOD mice.1,25-Dihydroxyvitamin D3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patientsExpansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes.Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development.Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptideNonapoptotic and extracellular activity of granzyme B mediates resistance to regulatory T cell (Treg) suppression by HLA-DR-CD25hiCD127lo Tregs in multiple sclerosis and in response to IL-6.T cell-driven initiation and propagation of autoimmune diabetesImmunological Basis for Rapid Progression of Diabetes in Older NOD Mouse Recipients Post BM-HSC TransplantationHarnessing memory adaptive regulatory T cells to control autoimmunity in type 1 diabetes.
P2860
Q21562482-EC776E69-1BEB-4C5B-BF1B-AF10891985B3Q24633549-9A20260D-3CB6-4DF4-95A2-DBE544F2649FQ26744624-CC4B0282-466F-4F86-8EE2-6B4AFECB089EQ26772723-7E70512E-A938-4909-8218-EFF00C6055BBQ26777557-9F047253-3212-4A6D-8CBF-B9BF3A8CC37CQ26853599-14BA1716-9DC9-4491-8F71-3C1A77606774Q28071490-76698E36-4719-4690-B5C8-46F6406B6372Q28080791-1AF4A361-93D4-4164-853F-2E93A34327D9Q28281029-CF7C5C3A-58DD-41C5-83C0-FB663290F41DQ30276673-FF3F53EA-9B99-4061-81EC-1CE3DA1178D7Q33604570-02CF26BB-C8CF-46B2-9936-3459BC89B323Q33786819-EA8F7DA1-2625-4897-96A3-47C1563C65BEQ33811669-96607E0F-8F30-4353-8D84-9BCBA2D44FBFQ33818896-3EBAA1A2-E51E-4580-9F71-5B384D766DD5Q33829714-690FEAD2-437A-42DB-9764-9E7F12AC1832Q33907609-A159056C-74D0-4E02-98D9-1D09D2955357Q33955180-2D3E382C-5CA2-415B-91BB-F285C3B1A3C3Q34072331-68F024C2-861F-463C-80D9-0632DDD66AEBQ34384366-3F8B6857-6B38-4CD1-8DAD-C21A353DA78DQ34586781-CEBBA287-BD70-41DD-BE29-3F6BD6ED12CFQ34615216-F4DA2177-A677-46F8-BC42-BC426F3A82C0Q34646607-D4275E0C-EC7B-49C8-9692-D03AA81E3BCDQ34950622-0AD3B026-F16C-476F-8E9C-FE3578AC9A26Q34969823-C3FC9B04-2D34-4A4A-B846-0855B58E4039Q34974448-3795F4BB-F8ED-44CA-8A38-4B9672B1A31FQ35008222-0F24687F-A0DF-4BE0-A7C2-BBEF76B00618Q35041294-1AF40CCA-2531-4557-A98F-77615E74FFDCQ35094156-938248D0-8A8A-45C8-9CAC-A40087D0633CQ35123513-FD30BA69-5074-4098-91F8-3B5003E99B8AQ35178495-28C7925A-2211-423A-9C31-F1151DE42B41Q35180105-BC0F828F-2E80-4052-AADA-EB70B1AE647DQ35180980-384C63D9-8468-40C7-B992-8000C5C0E7CCQ35298711-F9C5D7C2-0D64-4050-BC28-90EC12A75F46Q35405076-1EF81EF7-10DA-4686-8378-BABA437A331EQ35431818-73107CA1-E02F-4ABC-BF11-039023EABAA1Q35563587-C77A012F-60C1-4146-B09C-7513F861DFABQ35595880-AD0ECAFB-031C-49E8-9151-9B4C27580DAAQ35597162-1A65DB0D-8E81-4389-8C94-91E15E831592Q35645163-25E0A7C1-A93F-4B59-9253-6708B582493DQ35716720-04877F2E-8BC6-48FD-A6C8-1EDED327DD49
P2860
The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The effector T cells of diabet ...... D4+ FOXP3+ regulatory T cells.
@en
type
label
The effector T cells of diabet ...... D4+ FOXP3+ regulatory T cells.
@en
prefLabel
The effector T cells of diabet ...... D4+ FOXP3+ regulatory T cells.
@en
P2093
P2860
P1476
The effector T cells of diabet ...... D4+ FOXP3+ regulatory T cells.
@en
P2093
Anya Schneider
Carla Greenbaum
Catherine Pihoker
Jane H Buckner
Mary Rieck
Srinath Sanda
P2860
P304
P356
10.4049/JIMMUNOL.181.10.7350
P407
P577
2008-11-01T00:00:00Z