Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.
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Defining the blanks--pharmacochaperoning of SLC6 transporters and ABC transportersPharmacological chaperoning: a primer on mechanism and pharmacologyThe Development of Screening Methods to Identify Drugs to Limit ER Stress Using Wild-type and Mutant Serotonin TransporterStructure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.Platelet serotonin transporter function predicts default-mode network activityProbing binding pocket of serotonin transporter by single molecular force spectroscopy on living cells.Axonal targeting of the serotonin transporter in cultured rat dorsal raphe neurons is specified by SEC24C-dependent export from the endoplasmic reticulumInside job: ligand-receptor pharmacology beneath the plasma membrane.Sequence determinants of the Caenhorhabditis elegans dopamine transporter dictating in vivo axonal export and synaptic localization.Pharmacological Chaperones of the Dopamine Transporter Rescue Dopamine Transporter Deficiency Syndrome Mutations in Heterologous Cells.Tracking single serotonin transporter molecules at the endoplasmic reticulum and plasma membraneCronobacter sakazakii infection alters serotonin transporter and improved fear memory retention in the rat.Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones.Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates.Switching the clientele: a lysine residing in the C terminus of the serotonin transporter specifies its preference for the coat protein complex II component SEC24CA salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter.A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter.How does the carboxyl terminus assist folding and ER export of the serotonin transporter?Characterising the interaction between the COPII component SEC24C and the human serotonin transporter.An unfolding story: Small molecules remedy misfolded monoamine transporters.Pharmacochaperoning in a Drosophila model system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism.Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters.SLC6 Transporter Folding Diseases and Pharmacochaperoning.The Dopamine Transporter Recycles via a Retromer-Dependent Postendocytic Mechanism: Tracking Studies Using a Novel Fluorophore-Coupling Approach.Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain.
P2860
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P2860
Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.
description
2010 nî lūn-bûn
@nan
2010年の論文
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2010年論文
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2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
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2010年論文
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2010年论文
@wuu
2010年论文
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2010年论文
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name
Mutations in the carboxyl-term ...... ir folding of the transporter.
@en
type
label
Mutations in the carboxyl-term ...... ir folding of the transporter.
@en
prefLabel
Mutations in the carboxyl-term ...... ir folding of the transporter.
@en
P2093
P2860
P50
P356
P1476
Mutations in the carboxyl-term ...... air folding of the transporter
@en
P2093
Ali El-Kasaby
Elisabeth Malle
Herwig Just
Oliver Kudlacek
P2860
P304
39201-39210
P356
10.1074/JBC.M110.118000
P407
P577
2010-10-02T00:00:00Z