Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice.
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Chylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defectsChylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipaseGPIHBP1 is responsible for the entry of lipoprotein lipase into capillariesGPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in miceGlycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 and the intravascular processing of triglyceride-rich lipoproteinsPalmoplantar keratoderma along with neuromuscular and metabolic phenotypes in Slurp1-deficient miceThe ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolismUnexpected expression pattern for glycosylphosphatidylinositol-anchored HDL-binding protein 1 (GPIHBP1) in mouse tissues revealed by positron emission tomography scanning.GPIHBP1 and lipolysis: an update.Deletion of the basement membrane heparan sulfate proteoglycan type XVIII collagen causes hypertriglyceridemia in mice and humansMultimerization of glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) and familial chylomicronemia from a serine-to-cysteine substitution in GPIHBP1 Ly6 domainEarly hepatic insulin resistance precedes the onset of diabetes in obese C57BLKS-db/db mice.Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia.GPIHBP1 and the processing of triglyceride-rich lipoproteinsGPIHBP1, an endothelial cell transporter for lipoprotein lipase.Cholesterol intake modulates plasma triglyceride levels in glycosylphosphatidylinositol HDL-binding protein 1-deficient mice.Whole-exome sequencing reveals GPIHBP1 mutations in infantile colitis with severe hypertriglyceridemia.Binding preferences for GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cellsEquivalent binding of wild-type lipoprotein lipase (LPL) and S447X-LPL to GPIHBP1, the endothelial cell LPL transporter.Genetic determinants of plasma triglyceridesPPARγ regulates expression of carbohydrate sulfotransferase 11 (CHST11/C4ST1), a regulator of LPL cell surface binding.Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion.Intermittent hypoxia inhibits clearance of triglyceride-rich lipoproteins and inactivates adipose lipoprotein lipase in a mouse model of sleep apnoea.Deletion of GPIHBP1 causing severe chylomicronemiaNew wrinkles in lipoprotein lipase biology.Acute hypoxia induces hypertriglyceridemia by decreasing plasma triglyceride clearance in mice.The ddY mouse: a model of postprandial hypertriglyceridemia in response to dietary fatAssessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells.Biochemistry and pathophysiology of intravascular and intracellular lipolysis.The metabolism of triglyceride-rich lipoproteins revisited: new players, new insight.Mobility of "HSPG-bound" LPL explains how LPL is able to reach GPIHBP1 on capillaries.GPIHBP1 and Plasma Triglyceride Metabolism.The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries.ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors.Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes.Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice.Functional validation of GPIHBP1 and identification of a functional mutation in GPIHBP1 for milk fat traits in dairy cattleA new monoclonal antibody, 4-1a, that binds to the amino terminus of human lipoprotein lipase.Plasma apolipoprotein AV levels in mice are positively associated with plasma triglyceride levels.
P2860
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P2860
Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Abnormal patterns of lipoprote ...... sma in GPIHBP1-deficient mice.
@en
type
label
Abnormal patterns of lipoprote ...... sma in GPIHBP1-deficient mice.
@en
prefLabel
Abnormal patterns of lipoprote ...... sma in GPIHBP1-deficient mice.
@en
P2093
P2860
P356
P1476
Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice
@en
P2093
André Bensadoun
Anne P Beigneux
Geesje M Dallinga-Thie
Jeffrey D Esko
Joseph R Bishop
Kristan Melford
Kristine Estrada
Loren G Fong
Michael M Weinstein
P2860
P304
34511-34518
P356
10.1074/JBC.M806067200
P407
P577
2008-10-08T00:00:00Z