The box1 domain of the erythropoietin receptor specifies Janus kinase 2 activation and functions mitogenically within an interleukin 2 beta-receptor chimera.
about
JAK2 activation by growth hormone and other cytokinesA region of the beta subunit of the interferon alpha receptor different from box 1 interacts with Jak1 and is sufficient to activate the Jak-Stat pathway and induce an antiviral stateErythropoietin and Friend virus gp55 activate different JAK/STAT pathways through the erythropoietin receptor in erythroid cellsThe first alpha helix of interleukin (IL)-2 folds as a homotetramer, acts as an agonist of the IL-2 receptor beta chain, and induces lymphokine-activated killer cellsJanus kinases: components of multiple signaling pathways.Erythropoietin in human milk: physiology and role in infant health.Jak2-Stat5 interactions analyzed in yeast.Homodimerization of the human interleukin 4 receptor alpha chain induces Cepsilon germline transcripts in B cells in the absence of the interleukin 2 receptor gamma chain.Intracellular signalling pathways activated by leptin.EPO receptor circuits for primary erythroblast survivalRole of adipokines signaling in the modulation of T cells function.Leptin signaling: A key pathway in immune responses.Angiotensin II stimulates proliferation of normal early erythroid progenitors.An interleukin (IL)-13 receptor lacking the cytoplasmic domain fails to transduce IL-13-induced signals and inhibits responses to IL-4.Mitogenic signaling and inhibition of apoptosis via the erythropoietin receptor Box-1 domain.Prediction of the structure of human Janus kinase 2 (JAK2) comprising the two carboxy-terminal domains reveals a mechanism for autoregulation.Epo-induced hemoglobinization of SKT6 cells is mediated by minimal cytoplasmic domains of the Epo or prolactin receptors without modulation of GATA-1 or EKLF.
P2860
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P2860
The box1 domain of the erythropoietin receptor specifies Janus kinase 2 activation and functions mitogenically within an interleukin 2 beta-receptor chimera.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The box1 domain of the erythro ...... eukin 2 beta-receptor chimera.
@en
type
label
The box1 domain of the erythro ...... eukin 2 beta-receptor chimera.
@en
prefLabel
The box1 domain of the erythro ...... eukin 2 beta-receptor chimera.
@en
P2093
P2860
P356
P1476
The box1 domain of the erythro ...... eukin 2 beta-receptor chimera.
@en
P2093
P2860
P304
16472-16476
P356
10.1074/JBC.271.28.16472
P407
P577
1996-07-01T00:00:00Z