Vasoactive intestinal peptide (VIP)1 receptor. Three nonadjacent amino acids are responsible for species selectivity with respect to recognition of peptide histidine isoleucineamide.
about
VPAC receptors: structure, molecular pharmacology and interaction with accessory proteinsIdentification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptideVPAC receptors for VIP and PACAPThe human vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide receptor 1 (VPAC1) promoter: characterization and role in receptor expression during enterocytic differentiation of the colon cancer cell line Caco-2Cl.20Cloning and functional characterization of the human VIP1/PACAP receptor promoter.Human VPAC1 receptor selectivity filter. Identification of a critical domain for restricting secretin binding.The VPAC1 receptor: structure and function of a class B GPCR prototype.Molecular basis for agonist selectivity and activation of the orphan bombesin receptor subtype 3 receptor.Molecular basis for the selectivity of the mammalian bombesin peptide, neuromedin B, for its receptorStructural and functional insights into the juxtamembranous amino-terminal tail and extracellular loop regions of class B GPCRs.Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivityEvidence for a direct interaction between the Thr11 residue of vasoactive intestinal polypeptide and Tyr184 located in the first extracellular loop of the VPAC2 receptor.Potentiation of the inhibitory effect of growth hormone-releasing hormone antagonists on PC-3 human prostate cancer by bombesin antagonists indicative of interference with both IGF and EGF pathways.Transmembrane residues together with the amino terminus limit the response of the parathyroid hormone (PTH) 2 receptor to PTH-related peptide.VIP enhances both pre- and postsynaptic GABAergic transmission to hippocampal interneurones leading to increased excitatory synaptic transmission to CA1 pyramidal cells.Domains determining agonist selectivity in chimaeric VIP2 (VPAC2)/PACAP (PAC1) receptorsAnalogues of VIP, helodermin, and PACAP discriminate between rat and human VIP1 and VIP2 receptors.Characterization of a novel VPAC(1) selective agonist and identification of the receptor domains implicated in the carboxyl-terminal peptide recognition.The human VPAC1 receptor: three-dimensional model and mutagenesis of the N-terminal domain.Transglutaminase-mediated polyamination of vasoactive intestinal peptide (VIP) Gln16 residue modulates VIP/PACAP receptor activity.Identification of cytoplasmic domains of hVPAC1 receptor required for activation of adenylyl cyclase. Crucial role of two charged amino acids strictly conserved in class II G protein-coupled receptors.Photoaffinity labeling demonstrates physical contact between vasoactive intestinal peptide and the N-terminal ectodomain of the human VPAC1 receptor.Diffuse pharmacophoric domains of vasoactive intestinal peptide (VIP) and further insights into the interaction of VIP with the N-terminal ectodomain of human VPAC1 receptor by photoaffinity labeling with [Bpa6]-VIP.Peptide agonist docking in the N-terminal ectodomain of a class II G protein-coupled receptor, the VPAC1 receptor. Photoaffinity, NMR, and molecular modeling.
P2860
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P2860
Vasoactive intestinal peptide (VIP)1 receptor. Three nonadjacent amino acids are responsible for species selectivity with respect to recognition of peptide histidine isoleucineamide.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Vasoactive intestinal peptide ...... ide histidine isoleucineamide.
@en
type
label
Vasoactive intestinal peptide ...... ide histidine isoleucineamide.
@en
prefLabel
Vasoactive intestinal peptide ...... ide histidine isoleucineamide.
@en
P2093
P2860
P356
P1476
Vasoactive intestinal peptide ...... tide histidine isoleucineamide
@en
P2093
C Rouyer-Fessard
J J Maoret
M Laburthe
P2860
P304
12795-12800
P356
10.1074/JBC.271.22.12795
P407
P577
1996-05-01T00:00:00Z