Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription.

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Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease.Requirement for NF-κB in maintenance of molecular and behavioral circadian rhythms in mice Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2

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Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription.

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Bmal1 regulates inflammatory r ...... ng enhancer RNA transcription.

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Bmal1 regulates inflammatory r ...... ng enhancer RNA transcription.

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Bmal1 regulates inflammatory r ...... ng enhancer RNA transcription.

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Bmal1 regulates inflammatory r ...... ng enhancer RNA transcription.

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Atsushi Iwama

http://www.w3.org/2001/XMLSchema#string

Hitoshi Okamura

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Ichiro Manabe

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Motohiko Oshima

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Shigeki Shimba

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Shinichiro Hayashi

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Takayuki Isagawa

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Yumiko Oishi

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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

An integrated encyclopedia of DNA elements in the human genome

Circadian misalignment augments markers of insulin resistance and inflammation, independently of sleep loss

The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene

Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

Molecular control of activation and priming in macrophages

Deficient of a clock gene, brain and muscle Arnt-like protein-1 (BMAL1), induces dyslipidemia and ectopic fat formation

Coordination of circadian timing in mammals

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s41598-017-07100-3

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7086

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scholarly article

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10.1038/S41598-017-07100-3

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English

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2017-08-01T00:00:00Z

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28765524

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5539165

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Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription.

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P2860

P2860

Bmal1 regulates inflammatory responses in macrophages by modulating enhancer RNA transcription.

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P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P577

P698

P932