Phosphatidic acid: a lipid messenger involved in intracellular and extracellular signalling.
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Identification and characterization of two splice variants of human diacylglycerol kinase etaAlternative splicing of the human diacylglycerol kinase delta gene generates two isoforms differing in their expression patterns and in regulatory functionsIdentification of the phosphatidic acid phosphatase type 2a isozyme as an androgen-regulated gene in the human prostatic adenocarcinoma cell line LNCaPThe plasma membrane translocation of diacylglycerol kinase delta1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domainSalt and drought stress signal transduction in plantsExpression of lysophosphatidic acid acyltransferase beta (LPAAT-beta) in ovarian carcinoma: correlation with tumour grading and prognosisIsolation and characterization of the Saccharomyces cerevisiae DPP1 gene encoding diacylglycerol pyrophosphate phosphatase.Biological role of the N-formyl peptide receptorsCloning of a novel human diacylglycerol kinase (DGKtheta) containing three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain.Involvement of a novel Arabidopsis phospholipase D, AtPLDdelta, in dehydration-inducible accumulation of phosphatidic acid in stress signalling.Phosphohydrolase and transphosphatidylation reactions of two Streptomyces phospholipase D enzymes: covalent versus noncovalent catalysis.The C terminus of mammalian phospholipase D is required for catalytic activity.Phospholipase D1 mediates TNFalpha-induced inflammation in a murine model of TNFalpha-induced peritonitis.Diacylglycerol kinase gamma serves as an upstream suppressor of Rac1 and lamellipodium formation.Mammalian Mg2+-independent phosphatidate phosphatase (PAP2) displays diacylglycerol pyrophosphate phosphatase activity.Drug analysis based on signaling responses to G-protein-coupled receptors.Diacylglycerol Kinase Inhibition and Vascular FunctionDistinct expression and localization of the type II diacylglycerol kinase isozymes δ, η and κ in the mouse reproductive organs.Expression and localization of type II diacylglycerol kinase isozymes δ and η in the developing mouse brain.The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells.Phosphatidic acid regulation of PIPKI is critical for actin cytoskeletal reorganization.G protein-coupled receptor FPR1 as a pharmacologic target in inflammation and human glioblastoma.Bacterial protein toxins and lipids: role in toxin targeting and activity.The Pleckstrin Homology Domain of Diacylglycerol Kinase η Strongly and Selectively Binds to Phosphatidylinositol 4,5-BisphosphateMolecular heterogeneity of phospholipase D (PLD). Cloning of PLDgamma and regulation of plant PLDgamma, -beta, and -alpha by polyphosphoinositides and calcium.Factor VII and protein C are phosphatidic acid-binding proteins.Phospholipase D in platelets and other cells.Recent progress on type II diacylglycerol kinases: the physiological functions of diacylglycerol kinase δ, η and κ and their involvement in disease.Water deficit triggers phospholipase D activity in the resurrection plant Craterostigma plantagineum.Tracking Diacylglycerol and Phosphatidic Acid Pools in Budding Yeast.Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer.Induction of filopodia-like protrusions in N1E-115 neuroblastoma cells by diacylglycerol kinase γ independent of its enzymatic activity: potential novel function of the C-terminal region containing the catalytic domain of diacylglycerol kinase γ.Diacylglycerol kinase-dependent formation of phosphatidic acid molecular species during interleukin-2 activation in CTLL-2 T-lymphocytes.EF-hand motifs of diacylglycerol kinase α interact intra-molecularly with its C1 domains.Activation of phospholipase D activity in transforming growth factor-beta-induced cell growth inhibition.Phospholipase D and its product, phosphatidic acid, mediate agonist-dependent raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway.Specific inhibition of phorbol ester-stimulated phospholipase D by Clostridium sordellii lethal toxin and Clostridium difficile toxin B-1470 in HEK-293 cells. Restoration by Ral GTPases.Lysophosphatidic acid stimulates phospholipase D activity and cell proliferation in PC-3 human prostate cancer cells.Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid.
P2860
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P2860
Phosphatidic acid: a lipid messenger involved in intracellular and extracellular signalling.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Phosphatidic acid: a lipid mes ...... and extracellular signalling.
@en
type
label
Phosphatidic acid: a lipid mes ...... and extracellular signalling.
@en
prefLabel
Phosphatidic acid: a lipid mes ...... and extracellular signalling.
@en
P1433
P1476
Phosphatidic acid: a lipid mes ...... and extracellular signalling.
@en
P2093
P304
P356
10.1016/0898-6568(95)00076-3
P577
1996-08-01T00:00:00Z