The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells.
about
Hepatitis B virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cellsInterferon Regulatory Factor 1 (IRF-1) induces p21(WAF1/CIP1) dependent cell cycle arrest and p21(WAF1/CIP1) independent modulation of survivin in cancer cellsThe Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation.Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growthTReP-132 controls cell proliferation by regulating the expression of the cyclin-dependent kinase inhibitors p21WAF1/Cip1 and p27Kip1Interaction of human thymidine kinase 1 with p21(Waf1)The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phaseHuR regulates p21 mRNA stabilization by UV lightThe gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoterMotif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulationCloning and partial characterization of the mouse glutamine:fructose-6-phosphate amidotransferase (GFAT) gene promoterCleavage of p21/WAF1/CIP1 by proteinase 3 modulates differentiation of a monocytic cell line. Molecular analysis of the cleavage site.Characterization of the neuropilin-1 promoter; gene expression is mediated by the transcription factor Sp1.Activation of the p21WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites.Down-regulation of human topoisomerase IIalpha expression correlates with relative amounts of specificity factors Sp1 and Sp3 bound at proximal and distal promoter regionsNatural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene.Regulation of myelin basic protein gene transcription by Sp1 and Puralpha: evidence for association of Sp1 and Puralpha in brain.Neu differentiation factor stimulates phosphorylation and activation of the Sp1 transcription factorBCR-ABL but not JAK2 V617F inhibits erythropoiesis through the Ras signal by inducing p21CIP1/WAF1.The p21-dependent radiosensitization of human breast cancer cells by MLN4924, an investigational inhibitor of NEDD8 activating enzyme.Overexpression of HMGB1 in melanoma predicts patient survival and suppression of HMGB1 induces cell cycle arrest and senescence in association with p21 (Waf1/Cip1) up-regulation via a p53-independent, Sp1-dependent pathwayCytosolic retention of phosphorylated extracellular signal-regulated kinase and a Rho-associated kinase-mediated signal impair expression of p21(Cip1/Waf1) in phorbol 12-myristate-13- acetate-induced apoptotic cellsDual effects of hepatitis C virus Core protein on the transcription of cyclin-dependent kinase inhibitor p21 gene.The cyclooxygenase inhibitor sulindac sulfide inhibits EP4 expression and suppresses the growth of glioblastoma cells.Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription.Identification of poly(ADP-ribose) polymerase-1 as a cell cycle regulator through modulating Sp1 mediated transcription in human hepatoma cells.Transcriptional regulation of the cyclin-dependent kinase inhibitor 1A (p21) gene by NFI in proliferating human cellsCyproheptadine, an antihistaminic drug, inhibits proliferation of hepatocellular carcinoma cells by blocking cell cycle progression through the activation of P38 MAP kinase.Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members.Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility.Protein kinase Calpha-induced derepression of the human luteinizing hormone receptor gene transcription through ERK-mediated release of HDAC1/Sin3A repressor complex from Sp1 sites.Redox-regulation of Erk1/2-directed phosphatase by reactive oxygen species: role in signaling TPA-induced growth arrest in ML-1 cellsSp1 and the 'hallmarks of cancer'.Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein.Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites.A Sp1 binding site of the tumor necrosis factor alpha promoter functions as a nitric oxide response element.Sp1 and Sp3 are involved in up-regulation of human deoxyribonuclease II transcription during differentiation of HL-60 cells.3,3'-Diindolylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression.Role of the translational repressor 4E-BP1 in the regulation of p21(Waf1/Cip1) expression by retinoids.Unique induction of p21(WAF1/CIP1)expression by vinorelbine in androgen-independent prostate cancer cells.
P2860
Q22254707-5523D238-2260-4C2A-A0D6-2CE8D0BDB761Q24300739-7FA79F09-5D42-4A3D-B6EE-AEF7D83C7C2CQ24310788-452BC2ED-0647-4AB4-8AD0-4B8D4F209189Q24316065-723390D3-A457-4BFA-A358-B5956E4A8DEFQ24529076-1ED1287D-185B-4BD8-A85E-55B75B16D12CQ24532825-2B4AC705-1606-4755-8B8F-FDA344B9ED96Q24533294-4E430A52-53A9-4DFE-844B-3F9E09C39D77Q24554331-0B647947-A147-4F1B-8D18-83967A2CF6D9Q24653488-ADE731C1-D9C6-4CEF-9610-3D65EB3AE23AQ26775592-1BCE7468-EE1C-4D2F-9741-6865D8C2C52CQ28587198-E4B87DB5-CBAE-4031-927A-8412B274A8ACQ30855520-A0005615-EE85-499D-8B97-0087882CF915Q31131003-F6B59535-D17A-49A5-A19F-F39221CD9AFBQ31750307-CB7DECDD-27A6-44A9-98B2-BF102136C503Q33285072-9360AEBB-E847-45DE-B656-DEC9E93F490CQ33833014-2F834BE0-97F8-4124-A8B6-6A8E885408C5Q33871779-A6ACD8A3-BBB3-40D4-8154-0993DA4FD9DEQ33957454-2F174E72-75AB-4FC4-A0AB-BC1B164428ADQ34181572-69F35428-C37C-4169-B1C3-C583F1FA5390Q34212168-85A37C12-22AA-400A-A08C-83334338472AQ34227734-BF477CD8-2033-4756-98AD-191F8F0787A9Q34325742-79DB9920-D640-4179-8103-F2AF475A7F1FQ34534800-A485CFB1-6204-4506-82FE-F7F43D4A182DQ34614124-4C93B14A-A7C7-43BC-9A26-9161FDC8EF5CQ34632672-F30966EF-D525-4F3D-B911-54198B7AB4CCQ35075466-79F9C2FB-F84B-477B-B02C-9E807E3D0936Q35225482-A67007BC-3FEF-4004-8936-0E082D3E6C90Q35248527-237ECECD-1558-455A-B107-D4AF76B22DB8Q36486862-FE8DFE5D-B32D-4894-B069-DA77526757D7Q36568052-87DCF456-6440-4312-B54D-915BE053EF05Q36710187-8AC96AB5-FEBE-4310-BA0B-89323996070AQ36983415-288018C0-0429-4AD9-B8F7-9E7C07199EBCQ38267908-F2ADED38-306D-4A87-A70E-131E6C2830A2Q38300297-9D66C6C7-B708-4664-AA0C-8096808237AAQ38317596-33F35FE2-FA4B-4238-A5C9-962D9EF70C8DQ38318551-66EFFF3A-C77F-4ACE-A591-9D9E11112402Q38355603-1B691518-2DA3-4F60-9FC6-C699F6CF94D6Q38363872-410B55F5-407B-4D8E-B3AF-307C76C3338AQ38569361-64C6316D-83E5-4AA2-A5D2-9D591D2DF102Q38602505-5CBF1101-BE65-452C-BC67-1E11A6D85EBE
P2860
The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
The role of the transcription ...... 1 gene in U937 leukemic cells.
@en
type
label
The role of the transcription ...... 1 gene in U937 leukemic cells.
@en
prefLabel
The role of the transcription ...... 1 gene in U937 leukemic cells.
@en
P2093
P2860
P356
P1476
The role of the transcription ...... 1 gene in U937 leukemic cells.
@en
P2093
P2860
P304
P356
10.1074/JBC.271.2.901
P407
P577
1996-01-01T00:00:00Z