Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients.

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Clinical implications of genetic variation in carboxylesterase drug metabolism.

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Q49628042-3D768347-D1AB-449E-953C-0EF21567BD66

P2860

Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients.

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http://www.wikidata.org/entity/Q41242987

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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2017年學術文章

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name

Effect of carboxylesterase 1 S ...... te coronary syndrome patients.

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type

Item

label

Effect of carboxylesterase 1 S ...... te coronary syndrome patients.

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prefLabel

Effect of carboxylesterase 1 S ...... te coronary syndrome patients.

@en

P1476

Effect of carboxylesterase 1 S ...... te coronary syndrome patients.

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P2093

Bi-Lian Chen

http://www.w3.org/2001/XMLSchema#string

Fei-Yan Xiao

http://www.w3.org/2001/XMLSchema#string

Gan Zhou

http://www.w3.org/2001/XMLSchema#string

Hong-Hao Zhou

http://www.w3.org/2001/XMLSchema#string

Jian-Quan Luo

http://www.w3.org/2001/XMLSchema#string

Min Liu

http://www.w3.org/2001/XMLSchema#string

Shan Cao

http://www.w3.org/2001/XMLSchema#string

Wei Zhang

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P2860

Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis

Antiplatelet agents aspirin and clopidogrel are hydrolyzed by distinct carboxylesterases, and clopidogrel is transesterificated in the presence of ethyl alcohol

Activation of the antiviral prodrug oseltamivir is impaired by two newly identified carboxylesterase 1 variants

Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy

Surge in expression of carboxylesterase 1 during the post-neonatal stage enables a rapid gain of the capacity to activate the anti-influenza prodrug oseltamivir.

The role of human carboxylesterases in drug metabolism: have we overlooked their importance?

Examination of the carboxylesterase phenotype in human liver

Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation.

The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs.

P2888

s41598-017-07736-1

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scholarly article

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10.1038/S41598-017-07736-1

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English

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Zhao-Qian Liu

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2017-08-03T00:00:00Z

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28775293

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P921

clopidogrel

P932

5543069

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Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients.

about

P2860

P2860

Effect of carboxylesterase 1 S75N on clopidogrel therapy among acute coronary syndrome patients.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932