CD4:gp120:gp41 membrane complexCD4:Env gp120 with exposed coreceptor binding siteCD4:Env gp120 (second conformation change) complexCD4:Env gp120/gp41 fusion peptide complexCD4:Env gp120/gp41 insertion complexCD4:Env gp120/gp41 hairpin complexCD4:Lck ComplexCD4:Nef ComplexInternalized CD4:Nef:Clathrin-Coated Pit Adapter Protein:v-ATPaseArf1:Nef:endosomal CD4CD4:Vpu complexAntigen-bearing MHC Class II : TCR complex:CD4:LckAntigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505)Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4Defensins alpha 1-3:CD4CD4:IL16(1212-1332)AP-2 dileucine-containing cargoAP-2 dileucine-containing cargo [clathrin-coated vesicle membrane]Binding of gp120 of ENV oligomer to the host CD4Formation of a Nef:ARF1:CD4 complexAssociation of Vpu with CD4HNP1-3 bind CD4CD4 binds Interleukin-16
P527
P688
The phospholipid scramblases 1 and 4 are cellular receptors for the secretory leukocyte protease inhibitor and interact with CD4 at the plasma membraneHIV-1 envelope gp120 inhibits the monocyte response to chemokines through CD4 signal-dependent chemokine receptor down-regulationInhibition of tyrosine kinase activation blocks the down-regulation of CXC chemokine receptor 4 by HIV-1 gp120 in CD4+ T cellsConformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimeticThe transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chainCrystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC moleculeFcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infectionSignal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tailInteraction of p56lck with CD4 in the yeast two-hybrid systemRole of CD4 and CD8 in T cell activation and differentiationAdhesion versus coreceptor function of CD4 and CD8: role of the cytoplasmic tail in coreceptor activityA Zn2+ ion links the cytoplasmic tail of CD4 and the N-terminal region of LckCD4 dimers constitute the functional component required for T cell activationCross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation siteSTRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1Dimeric association and segmental variability in the structure of human CD4Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domainThe level of CD4 surface protein influences T cell selection in the thymusCD4 raft association and signaling regulate molecular clustering at the immunological synapse siteInteraction between CD4 and class II MHC molecules mediates cell adhesionThe CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lckCD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infectionStructure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist.
P921
Q50256457-5FD7328B-BE8C-475A-AA1B-2C9AFFCF9DE1Q50256460-32E25DAE-3718-48A8-BE80-93DBCB6F913EQ50256468-AFF5A342-8003-4D65-A363-3AB4EC79B7B5Q50256475-3C9BD0D0-944B-4E77-A594-1765904CC6C2Q50256481-C148B785-961C-4271-A0BA-373D0D0FA239Q50256486-2F0D2073-DEF8-48BC-A2A9-D9D370AA53CFQ50256700-BA9D47CB-F8AC-48BD-B2C1-D6EED5FC6FE8Q50256701-9FB4753D-B5D3-4807-A0DF-AAA153FAFFD3Q50256703-0231E6EE-2C33-4B4A-B330-678253D3FA29Q50256704-7BDC6FFE-6857-4F00-A8A7-D662EBB8B417Q50256710-84A2AB9B-8281-484E-B800-5DB8DB0B3BA6Q50259726-F27BA121-ADF4-4A60-BA76-CD5473A238EEQ50259751-BC512008-936D-4AE2-B427-C968D20AF9C8Q50259755-6C9C1CDA-3A27-45A5-813E-518C45257607Q50259758-9A696032-D3D8-4782-ACB8-32AB0EB8347AQ50259944-4FEB43C8-3079-429C-881D-557FA2995546Q50262233-5D6EA6AB-1956-40D2-92C5-091C0EEA8942Q50263748-3A7CCAEA-6A32-4F64-9589-12A36E2FC18AQ50275075-D8047331-FF58-4131-AEF5-DBE743EA71B0Q50275152-DA2C4E09-63BE-4103-99B5-9E37271BE2A6Q50289256-45AB715D-FC39-4D2F-9E48-C86665E69A5DQ50289444-DF005BFC-C488-4C52-8397-925FB4A29F5BQ50289450-56C8984E-47CB-4892-9D27-E30402B25709Q50292339-58749571-0565-47B0-B4D6-7802ACA00725Q50292976-0EC9216B-E78A-4EA3-9358-47D914237A34
P527
Q21143809-D9A4395B-5F4B-4F7E-AF48-55B224CED09DQ22003981-DEE8DD4E-3D01-4DFD-A4D5-31327392F607Q22009940-6F6A49AA-F249-4037-BE1D-7FAE9C9528CCQ22010407-F93DDF34-4391-4CA0-AFFF-4A4935E2D335Q24291295-AA0C5E04-6FB2-411A-B77C-CD7098256268Q24291640-2E954108-2AF9-438E-96EF-4F9B044A156DQ24292727-65542B6A-0A49-4E54-832D-04EF6E43F981Q24302036-8890B968-F405-4917-93BD-A4BFFA4F220DQ24303628-FACE474F-EFFE-43D0-A975-707F0E43F528Q24309394-7420B2FA-7AD0-41E9-8EC8-BE3AC7C19E09Q24315140-33E4EB7E-E0E8-435C-8F62-08BA918C96ECQ24316020-74B04A65-9F22-4849-A2C9-BD4F533C984DQ24319944-E1C1E97A-C2DC-41B9-82A5-B5ADF1E1C7D1Q24321802-DED6A292-66C1-46B4-9B07-5C7410D37C1BQ24324020-86F981E7-CC5D-47F1-A395-B5871C89FF2CQ24324340-423119C0-17FB-4E52-ADFE-AFD385B3FB34Q24336240-2F36E7BE-6292-466C-9C34-5C2032ABF522Q24336823-D4509731-1AF5-45E7-BF19-950FB3522AABQ24338747-8C43BACB-86D8-40AC-90FB-4AE544812DD4Q24339626-2A5D625C-C974-4EB6-8C4E-B7AE59183A4BQ28506433-F01B40D8-8FF2-4913-88AB-ABA155AFBB79Q28910367-578784BA-A9B1-42F6-BE91-713FF1B66698Q30358736-934786DF-EEE8-42FF-9A9C-099E428349FC
P921
description
Protein
@de
mammalian protein found in Homo sapiens
@en
mammalsk protein hos arten Homo sapiens
@nn
protein
@id
protein
@sv
proteinë
@sq
proteïne in CD4
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
CD4 molecule
@en
CD4
@ca
CD4
@cs
CD4
@da
CD4
@en-ca
CD4
@en-gb
CD4
@es
CD4
@fi
CD4
@fr
CD4
@gl
type
label
CD4 molecule
@en
CD4
@ca
CD4
@cs
CD4
@da
CD4
@en-ca
CD4
@en-gb
CD4
@es
CD4
@fi
CD4
@fr
CD4
@gl
altLabel
CD4 Antigens
@en
CD4 antigen (p55)
@en
CD4 receptor
@en
CD4
@de
CD4
@en
CD4
@nn
CD4
@zh
CD4+ T-lymfocyty
@cs
CD4+
@cs
CD4-antigen
@nn
prefLabel
CD4 molecule
@en
CD4
@ca
CD4
@cs
CD4
@da
CD4
@en-ca
CD4
@en-gb
CD4
@es
CD4
@fi
CD4
@fr
CD4
@gl
P361
P527
P637
P638
P672
P680
P681
P682
P705
P352
P486
P637
P646
P672
P2888
P31
P352
P486
P527
P637
NP_001181943
NP_001181944
NP_001181945
NP_001181946
NP_001369634
NP_001369635
NP_001369636
NP_001369643
P638
P646
P672
D12.776.543.750.705.852.420.810.500
D12.776.543.750.830.700.025
D23.050.301.264.894.100
D23.101.100.894.100
P680
P681
P682
P702
P703
P705
ENSP00000011653
ENSP00000440720
ENSP00000445167
P7260
8.A.23.2.1