Evidence that Sindbis virus NSP2 is an autoprotease which processes the virus nonstructural polyprotein.
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Cis-acting RNA elements at the 5' end of Sindbis virus genome RNA regulate minus- and plus-strand RNA synthesis.High-resolution functional mapping of the venezuelan equine encephalitis virus genome by insertional mutagenesis and massively parallel sequencingA single amino acid change in nsP1 attenuates neurovirulence of the Sindbis-group alphavirus S.A.AR86.Enzymatic Defects of the nsP2 Proteins of Semliki Forest Virus Temperature-Sensitive MutantsRegulation of Sindbis virus RNA replication: uncleaved P123 and nsP4 function in minus-strand RNA synthesis, whereas cleaved products from P123 are required for efficient plus-strand RNA synthesisGenetic analysis of the nsP3 region of Sindbis virus: evidence for roles in minus-strand and subgenomic RNA synthesisATPase and GTPase activities associated with Semliki Forest virus nonstructural protein nsP2Solubilization and immunoprecipitation of alphavirus replication complexesBiogenesis of type I cytopathic vacuoles in Semliki Forest virus-infected BHK cellsAssembly of functional Sindbis virus RNA replication complexes: requirement for coexpression of P123 and P34Roles of nonstructural polyproteins and cleavage products in regulating Sindbis virus RNA replication and transcriptionNuclear localization of Semliki Forest virus-specific nonstructural protein nsP2Processing the nonstructural polyproteins of sindbis virus: nonstructural proteinase is in the C-terminal half of nsP2 and functions both in cis and in transThe nsP3 macro domain is important for Sindbis virus replication in neurons and neurovirulence in miceKinetic, Mutational, and Structural Studies of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine ProteaseThe alphaviruses: gene expression, replication, and evolutionRequirements at the 3' end of the sindbis virus genome for efficient synthesis of minus-strand RNAIdentification of a dominant negative inhibitor of human zinc finger antiviral protein reveals a functional endogenous pool and critical homotypic interactions.Interaction of Sindbis virus non-structural protein 3 with poly(ADP-ribose) polymerase 1 in neuronal cells.Cleavage-site preferences of Sindbis virus polyproteins containing the non-structural proteinase. Evidence for temporal regulation of polyprotein processing in vivo.Regulation of nuclear transport of a plant potyvirus protein by autoproteolysis.Functional analysis of nsP3 phosphoprotein mutants of Sindbis virus.Comparison of two aquatic alphaviruses, salmon pancreas disease virus and sleeping disease virus, by using genome sequence analysis, monoclonal reactivity, and cross-infection.Cryo-electron tomography of rubella virus.Properly folded nonstructural polyprotein directs the semliki forest virus replication complex to the endosomal compartment.Requirement for the amino-terminal domain of sindbis virus nsP4 during virus infection.Alphavirus vectors and vaccination.Characterization of purified Sindbis virus nsP4 RNA-dependent RNA polymerase activity in vitro.Sindbis virus RNA-negative mutants that fail to convert from minus-strand to plus-strand synthesis: role of the nsP2 protein.Alphavirus nsP3 functions to form replication complexes transcribing negative-strand RNASindbis virus nsP1 functions in negative-strand RNA synthesisRole for conserved residues of sindbis virus nonstructural protein 2 methyltransferase-like domain in regulation of minus-strand synthesis and development of cytopathic infection.Rescue of Sindbis virus-specific RNA replication and transcription by using a vaccinia virus recombinant.Role for subgenomic mRNA in host translation inhibition during Sindbis virus infection of mammalian cells.Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymesSindbis virus RNA polymerase is degraded by the N-end rule pathway.Hypervariable domain of nonstructural protein nsP3 of Venezuelan equine encephalitis virus determines cell-specific mode of virus replication.Hypervariable domains of nsP3 proteins of New World and Old World alphaviruses mediate formation of distinct, virus-specific protein complexes.Template-dependent initiation of Sindbis virus RNA replication in vitro.Replicon vectors derived from Sindbis virus and Semliki forest virus that establish persistent replication in host cells.
P2860
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P2860
Evidence that Sindbis virus NSP2 is an autoprotease which processes the virus nonstructural polyprotein.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Evidence that Sindbis virus NS ...... rus nonstructural polyprotein.
@en
type
label
Evidence that Sindbis virus NS ...... rus nonstructural polyprotein.
@en
prefLabel
Evidence that Sindbis virus NS ...... rus nonstructural polyprotein.
@en
P1433
P1476
Evidence that Sindbis virus NS ...... rus nonstructural polyprotein.
@en
P2093
Schlesinger MJ
P304
P356
10.1016/0042-6822(89)90539-4
P407
P577
1989-07-01T00:00:00Z