Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate.
about
Candidate gene sequencing of LHX2, HESX1, and SOX2 in a large schizencephaly cohortInsights into the Biology and Therapeutic Applications of Neural Stem CellsSwitching modes in corticogenesis: mechanisms of neuronal subtype transitions and integration in the cerebral cortexMolecular underpinnings of prefrontal cortex development in rodents provide insights into the etiology of neurodevelopmental disordersGeneration of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue.The molecular and cellular signatures of the mouse eminentia thalami support its role as a signalling centre in the developing forebrain.Lhx2 is required for patterning and expansion of a distinct progenitor cell population committed to eye developmentCyclic expression of lhx2 regulates hair formationTumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivatorsArchitectural niche organization by LHX2 is linked to hair follicle stem cell functionExpression of Neurogenin 1 in mouse embryonic stem cells directs the differentiation of neuronal precursors and identifies unique patterns of down-stream gene expressionLoss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalonLhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortexTranscriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampusThe mammalian DM domain transcription factor Dmrta2 is required for early embryonic development of the cerebral cortexThe doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammalsExpression of the Lhx genes apterous and lim1 in an errant polychaete: implications for bilaterian appendage evolution, neural development, and muscle diversificationBone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior.Lhx2 regulates the development of the forebrain hem system.Broad integration of expression maps and co-expression networks compassing novel gene functions in the brain.Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal developmentBalanced Shh signaling is required for proper formation and maintenance of dorsal telencephalic midline structuresHedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosisMouse transgenesis identifies conserved functional enhancers and cis-regulatory motif in the vertebrate LIM homeobox gene Lhx2 locusTranscriptional regulation of enhancers active in protodomains of the developing cerebral cortexLmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hemLong noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes.LIM-homeobox gene Lhx5 is required for normal development of Cajal-Retzius cellsInducible genetic lineage tracing of cortical hem derived Cajal-Retzius cells reveals novel properties.Lhx2 and Lhx9 determine neuronal differentiation and compartition in the caudal forebrain by regulating Wnt signaling.Lhx2 regulates bone remodeling in mice by modulating RANKL signaling in osteoclasts.FGF8 acts as a classic diffusible morphogen to pattern the neocortex.MACF1 regulates the migration of pyramidal neurons via microtubule dynamics and GSK-3 signalingThe cortical hem regulates the size and patterning of neocortexLhx2 regulates a cortex-specific mechanism for barrel formation.Discrete domains of gene expression in germinal layers distinguish the development of gyrencephaly.Ofd1 controls dorso-ventral patterning and axoneme elongation during embryonic brain development.Neurogenesis in the embryonic and adult brain: same regulators, different rolesModeling human cortical development in vitro using induced pluripotent stem cells.The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation.
P2860
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P2860
Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Lhx2 selector activity specifi ...... es hippocampal organizer fate.
@en
type
label
Lhx2 selector activity specifi ...... es hippocampal organizer fate.
@en
prefLabel
Lhx2 selector activity specifi ...... es hippocampal organizer fate.
@en
P2093
P2860
P50
P356
P1433
P1476
Lhx2 selector activity specifi ...... ses hippocampal organizer fate
@en
P2093
Ben Martynoga
Jolly Paul
Karla E Hirokawa
Lisa A Flanagan
Mark V Mai
Nandini Gokulchandran
Prasad R V Satyaki
Satyadeep Chikbire
Shubha Tole
Vishakha S Mangale
P2860
P304
P356
10.1126/SCIENCE.1151695
P407
P577
2008-01-01T00:00:00Z