Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.
about
Synergistic antitumor activity of oncolytic reovirus and chemotherapeutic agents in non-small cell lung cancer cellsGranzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent mannerGranzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysisGranzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicksThe human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosisHMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme AIn vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domainsIdentification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosisA cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytesMolecular cloning, sequence, expression, and processing of the interleukin 16 precursorICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme BCaspases: the executioners of apoptosisCaspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis.Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosisA quarter century of granzymesRecombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of themSAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosisGraBCas: a bioinformatics tool for score-based prediction of Caspase- and Granzyme B-cleavage sites in protein sequences.Cloning CTL-Specific Genes (And Now for Something Completely Differential)Advantages and clinical applications of natural killer cells in cancer immunotherapyThe unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccinesCrystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residueStructure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteasesStructure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketoneSurvivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell deathGranzyme M mediates a novel form of perforin-dependent cell deathProcessing and activation of pro-interleukin-16 by caspase-3ERICE, a novel FLICE-activatable caspaseFas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signalingActivation of caspases in intestinal villus epithelial cells of normal and nematode infected ratsCytotoxic proteins and therapeutic targets in severe cutaneous adverse reactionsEssential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changesApoptosis: molecular regulation of cell deathActivation of caspase-2 in apoptosisA combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosisGranzyme B enters the mitochondria in a Sam50-, Tim22- and mtHsp70-dependent manner to induce apoptosis.
P2860
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P2860
Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.
@en
type
label
Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.
@en
prefLabel
Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.
@en
P2093
P356
P1433
P1476
Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.
@en
P2093
Bleackley RC
Nicholson DW
P2888
P304
P356
10.1038/377446A0
P407
P577
1995-10-01T00:00:00Z
P6179
1016593213