An in vivo study of Cdh1/APC in breast cancer formation.
about
Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.Nuclear translocation of Skp2 facilitates its destruction in response to TGFβ signaling.The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium.Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.The APC/C Ubiquitin Ligase: From Cell Biology to TumorigenesisInhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells.Genome-wide screen identifies novel machineries required for both ciliogenesis and cell cycle arrest upon serum starvation.TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.Activation of VCAM-1 and its associated molecule CD44 leads to increased malignant potential of breast cancer cells.APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy.The E3 ligase APC/C(Cdh1) promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth.Identifying mutual exclusivity across cancer genomes: computational approaches to discover genetic interaction and reveal tumor vulnerability.
P2860
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P2860
An in vivo study of Cdh1/APC in breast cancer formation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
An in vivo study of Cdh1/APC in breast cancer formation.
@en
type
label
An in vivo study of Cdh1/APC in breast cancer formation.
@en
prefLabel
An in vivo study of Cdh1/APC in breast cancer formation.
@en
P2093
P2860
P356
P1476
An in vivo study of Cdh1/APC in breast cancer formation
@en
P2093
Hiroyoshi Doihara
Takeo Fujita
P2860
P304
P356
10.1002/IJC.24399
P50
P577
2009-08-01T00:00:00Z