An aspartic acid residue important for voltage-dependent gating of human muscle chloride channels.
about
A mutation in autosomal dominant myotonia congenita affects pore properties of the muscle chloride channelMolecular basis for decreased muscle chloride conductance in the myotonic goatChannelopathies of skeletal muscle excitabilityImpaired surface membrane insertion of homo- and heterodimeric human muscle chloride channels carrying amino-terminal myotonia-causing mutationsInteraction of hydrophobic anions with the rat skeletal muscle chloride channel ClC-1: effects on permeation and gatingAnion pathway and potential energy profiles along curvilinear bacterial ClC Cl- pores: electrostatic effects of charged residuesConduction mechanisms of chloride ions in ClC-type channelsCLC channel function and dysfunction in health and disease.Simultaneous optical recording in multiple cells by digital holographic microscopy of chloride current associated to activation of the ligand-gated chloride channel GABA(A) receptor.Physiology and pathophysiology of CLC-1: mechanisms of a chloride channel disease, myotoniaClC1 chloride channel in myotonic dystrophy type 2 and ClC1 splicing in vitro.Subunit stoichiometry of human muscle chloride channels.Mechanism of ion permeation in skeletal muscle chloride channelsClC-1 chloride channel: Matching its properties to a role in skeletal muscle.Physiologic principles underlying ion channelopathies.CLC-0 and CFTR: chloride channels evolved from transporters.A single point mutation reveals gating of the human ClC-5 Cl-/H+ antiporter.ClC-K chloride channels: emerging pathophysiology of Bartter syndrome type 3.A tale of two CLCs: biophysical insights toward understanding ClC-5 and ClC-7 function in endosomes and lysosomes.Helix O modulates voltage dependency of CLC-1.Modulation of Chloride Currents in Human Lung Epithelial Cells Exposed to Exogenous Oxidative Stress.ClC Channels and Transporters: Structure, Physiological Functions, and Implications in Human Chloride Channelopathies.Voltage-dependent charge movement associated with activation of the CLC-5 2Cl-/1H+ exchanger.Molecular determinants of differential pore blocking of kidney CLC-K chloride channels.Carboxy-terminal truncations modify the outer pore vestibule of muscle chloride channelsThe role of the carboxyl terminus in ClC chloride channel function.Involvement of helices at the dimer interface in ClC-1 common gating.Temperature dependence of human muscle ClC-1 chloride channel.ClC-2 Cl- channels in human lung epithelia: activation by arachidonic acid, amidation, and acid-activated omeprazole.Identification of three cysteines as targets for the Zn2+ blockade of the human skeletal muscle chloride channel.Regulation of the human skeletal muscle chloride channel hClC-1 by protein kinase C.Permeation and block of the skeletal muscle chloride channel, ClC-1, by foreign anions.Pore-forming segments in voltage-gated chloride channels.Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathiespH-dependent interactions of Cd2+ and a carboxylate blocker with the rat C1C-1 chloride channel and its R304E mutant in the Sf-9 insect cell line.Mechanism of voltage-dependent gating in skeletal muscle chloride channels.Chloride channels take center stage in a muscular drama.The muscle chloride channel ClC-1 has a double-barreled appearance that is differentially affected in dominant and recessive myotonia.Inward rectification in ClC-0 chloride channels caused by mutations in several protein regions.Regulation of a hyperpolarization-activated chloride current in murine respiratory ciliated cells.
P2860
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P2860
An aspartic acid residue important for voltage-dependent gating of human muscle chloride channels.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
An aspartic acid residue impor ...... uman muscle chloride channels.
@en
type
label
An aspartic acid residue impor ...... uman muscle chloride channels.
@en
prefLabel
An aspartic acid residue impor ...... uman muscle chloride channels.
@en
P2093
P1433
P1476
An aspartic acid residue impor ...... uman muscle chloride channels.
@en
P2093
P304
P356
10.1016/0896-6273(95)90050-0
P407
P577
1995-08-01T00:00:00Z