High content screening of cortical neurons identifies novel regulators of axon growth.
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Isoform diversity and regulation in peripheral and central neurons revealed through RNA-SeqReorganization of Intact Descending Motor Circuits to Replace Lost Connections After InjuryTranscriptomic Approaches to Neural RepairNeurphologyJ: an automatic neuronal morphology quantification method and its application in pharmacological discoveryGene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord InjuryFear potentiated startle increases phospholipase D (PLD) expression/activity and PLD-linked metabotropic glutamate receptor mediated post-tetanic potentiation in rat amygdala.cJun promotes CNS axon growth.Challenges in small screening laboratories: implementing an on-demand laboratory information management system.Peripheral nerve graft with immunosuppression modifies gene expression in axotomized CNS neurons.Peripheral nervous system genes expressed in central neurons induce growth on inhibitory substrates.Increasing the Content of High-Content Screening: An OverviewA morphometric screen identifies specific roles for microtubule-regulating genes in neuronal development of P19 stem cellsMultiple transcription factor families regulate axon growth and regenerationPhenotypic assays to identify agents that induce reactive gliosis: a counter-screen to prioritize compounds for preclinical animal studiesThe Acquisition of Target Dependence by Developing Rat Retinal Ganglion Cells(1,2,3).Isoform diversity and its importance for axon regeneration.Expressing Constitutively Active Rheb in Adult Neurons after a Complete Spinal Cord Injury Enhances Axonal Regeneration beyond a Chondroitinase-Treated Glial Scar.Krüppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract.Heterogeneous intrastriatal pattern of proteins regulating axon growth in normal adult human brain.A chemical genetic approach identifies piperazine antipsychotics as promoters of CNS neurite growth on inhibitory substrates.Phenotypic Screening of Small-Molecule Inhibitors: Implications for Therapeutic Discovery and Drug Target Development in Traumatic Brain Injury.Identification of Intrinsic Axon Growth Modulators for Intact CNS Neurons after Injury.The assessment of adeno-associated vectors as potential intrinsic treatments for brainstem axon regeneration.Hyperactivated Stat3 boosts axon regeneration in the CNS.Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth.Intraspinal AAV Injections Immediately Rostral to a Thoracic Spinal Cord Injury Site Efficiently Transduces Neurons in Spinal Cord and Brain.Epigenetic profiling reveals a developmental decrease in promoter accessibility during cortical maturation in vivo.Mitochondrial Dynamics in Retinal Ganglion Cell Axon Regeneration and Growth Cone Guidance.Gene networks activated by specific patterns of action potentials in dorsal root ganglia neurons.Gene therapy approaches to enhancing plasticity and regeneration after spinal cord injury.Neurotrophic factors in combinatorial approaches for spinal cord regenerationSpinal cord injury and the neuron-intrinsic regeneration-associated gene program.Optimization of a 96-Well Electroporation Assay for Postnatal Rat CNS Neurons Suitable for Cost-Effective Medium-Throughput Screening of Genes that Promote Neurite OutgrowthIn vitro models of axon regeneration.The application of CRISPR technology to high content screening in primary neurons.Phenotypic screening with primary neurons to identify drug targets for regeneration and degeneration.High content analysis in amyotrophic lateral sclerosis.A gene network perspective on axonal regeneration.Dyrk kinases regulate phosphorylation of doublecortin, cytoskeletal organization, and neuronal morphology.The tumor suppressor HHEX inhibits axon growth when prematurely expressed in developing central nervous system neurons.
P2860
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P2860
High content screening of cortical neurons identifies novel regulators of axon growth.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
High content screening of cortical neurons identifies novel regulators of axon growth.
@en
type
label
High content screening of cortical neurons identifies novel regulators of axon growth.
@en
prefLabel
High content screening of cortical neurons identifies novel regulators of axon growth.
@en
P2860
P50
P1476
High content screening of cortical neurons identifies novel regulators of axon growth.
@en
P2093
Murray G Blackmore
Robin P Smith
P2860
P356
10.1016/J.MCN.2010.02.002
P577
2010-02-14T00:00:00Z