Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. - Wikidata - wikimedia - TriplyDB

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.

http://www.wikidata.org/entity/Q41330743

about

Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling Units Regulation of immune responses by prostaglandin E2 Lung cancer: a classic example of tumor escape and progression while providing opportunities for immunological intervention E-type prostanoid receptor 4 (EP4) in disease and therapy Prostaglandin E2 and T cells: friends or foes?Interleukin 17 contributes to the chronicity of inflammatory diseases such as rheumatoid arthritis Genetic requirements for the development and differentiation of interleukin-17-producing γδ T cells Regulation of T helper cell subsets by cyclooxygenases and their metabolites Lipid mediators are critical in resolving inflammation: a review of the emerging roles of eicosanoids in diabetes mellitus Inflammatory bowel disease PGE2 induces IL-6 in orbital fibroblasts through EP2 receptors and increased gene promoter activity: implications to thyroid-associated ophthalmopathy.Mesenchymal stem cells repress Th17 molecular program through the PD-1 pathway.Blockade of T cell contact-activation of human monocytes by high-density lipoproteins reveals a new pattern of cytokine and inflammatory genes.Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa.Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection Innate immune system and preeclampsia.Prostaglandin E2 promotes features of replicative senescence in chronically activated human CD8+ T cells.PGE2 receptor EP2 mediates the antagonistic effect of COX-2 on TGF-beta signaling during mammary tumorigenesis.Candidate chromosome 1 disease susceptibility genes for Sjogren's syndrome xerostomia are narrowed by novel NOD.B10 congenic mice.The functional -765G→C polymorphism of the COX-2 gene may reduce the risk of developing crohn's disease Cyclooxygenase-1 orchestrates germinal center formation and antibody class-switch via regulation of IL-17 Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells.Mucosal adjuvant activity of cholera toxin requires Th17 cells and protects against inhalation anthrax.Eicosanoids and cancer Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.Antagonizing arachidonic acid-derived eicosanoids reduces inflammatory Th17 and Th1 cell-mediated inflammation and colitis severity.Th1 and Th17 cells: adversaries and collaborators Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway The role of Th17 cytokines in primary mucosal immunity Prostaglandin I2 signaling drives Th17 differentiation and exacerbates experimental autoimmune encephalomyelitis.Fatty acids, lipid mediators, and T-cell function.T cells and stromal fibroblasts in human tumor microenvironments represent potential therapeutic targets.PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites Immune therapeutic targeting of glioma cancer stem cells.Effect of DiD Carbocyanine Dye Labeling on Immunoregulatory Function and Differentiation of Mice Mesenchymal Stem Cells.DNA methyltransferase inhibition accelerates the immunomodulation and migration of human mesenchymal stem cells.Translational mini-review series on Th17 cells: function and regulation of human T helper 17 cells in health and disease.Co-culture of human bronchial fibroblasts and CD4+ T cells increases Th17 cytokine signature.Effector and regulatory T-cell subsets in autoimmunity and tissue inflammation.Evidence for a role for interleukin-17, Th17 cells and iron homeostasis in protective immunity against tuberculosis in cynomolgus macaques

P2860

Q26744973-E587BD20-A577-4847-BA40-B6EF7E59FC49 Q26849305-ACCE8177-0228-47F7-870C-F80EB18FE190 Q26850218-2C51F2DA-66BD-43FC-B5A1-AE1E45A52D1A Q26851156-11BB135C-5704-4615-A21A-54582CC9341C Q27021151-E2B33C7C-4E2A-4A01-A0E2-FCA33E85E97C Q27023777-047EDD31-570A-4EC4-B339-CFB126EC708A Q27026048-97E75B80-15BA-4DFC-BBFE-74BFF7868BAD Q27026243-C7DACD3E-A608-4080-A562-DD6B22D1041A Q28080521-F59949A4-9949-4048-8016-29735C2411A1 Q29615500-34EA778C-A7E5-4592-A4FA-333C6A8D72D3 Q30994732-A17E8700-1680-41FA-85AD-8E845E164B77 Q31101562-F8B453D0-93E8-438E-9DB6-9768F6C59EC4 Q33535932-77E41167-88C7-4622-8BC7-0E1BA429871A Q33611067-5FB3185E-101B-4B85-83BA-32BB79FECB0A Q33651797-186D6528-DB58-430F-BAAC-5B12F1A75251 Q33658840-EF67857B-021A-4B4D-8FBA-43FEE84982EC Q33740540-BB1B68B5-1417-449B-A988-A771DBB8FB0E Q33752909-8D021A31-407F-449E-9DFF-4E1737114D64 Q33758184-8461B130-F4D2-4B77-BF0B-4637397285DE Q33760727-F94DD43B-C118-4368-9C43-AB6E3C3C970B Q33801163-79234F6F-8825-433D-8D04-FFAD34ABB889 Q33872546-6C92791E-8FFF-46AF-8097-69FBB773BE58 Q33935005-E8452804-F5F2-4080-84FF-F92C1E06C3BC Q33966203-2282EDA8-BA4B-47BD-9652-5F2E397F6D9D Q33982199-DAE9A759-955D-4F80-8BA2-4FE2C8E8A1DA Q34022356-D903EC9E-807A-41C3-9BA2-8D47ED072A49 Q34038557-BE45AEE0-F24F-4BD6-A047-136CCAF34866 Q34129168-C2AD108E-2600-4A7C-AB7F-F04F9E9A5D75 Q34151076-7A03B780-D170-4C97-95DA-089BFEDE9774 Q34270562-4929892E-76DE-4A2F-859F-A7AB852EB9B9 Q34330638-0C540CCC-7D9E-451F-813A-5D1BB91649BF Q34343664-E7557412-4E0C-4C03-B20B-19A22B589141 Q34541337-7EB389A3-9845-4F54-ACF8-67247C953AE9 Q34676437-980DC0FA-C315-4368-8A93-13408A7B105B Q34785710-01DEB988-8952-4909-BEF4-D399D5A8649A Q35011903-5471E97B-FFFB-4C3F-9019-76B00047BFC1 Q35012792-BBA3AC92-AC60-4EFB-A92C-5274AAB028F3 Q35069894-63276D2C-502C-43C3-88E0-CF6CB0A07E1B Q35084618-D4807255-42B4-43BE-B63E-E683B0E43946 Q35088532-02B1594E-F6BB-4E5A-A2CA-31AC57650AE2

P2860

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.

http://www.wikidata.org/entity/Q41330743

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

Prostaglandin E2 regulates Th1 ...... nd EP2/EP4 receptor signaling.

@en

type

label

Prostaglandin E2 regulates Th1 ...... nd EP2/EP4 receptor signaling.

@en

prefLabel

Prostaglandin E2 regulates Th1 ...... nd EP2/EP4 receptor signaling.

@en

P1433

Q41330743-6A8413B7-3FC2-47EA-84BC-6B719D66C9D5

P1476

Q41330743-D40E59AC-D3B6-454F-9ABE-856924B4912B

P2093

Q41330743-243987A3-82D1-4DC0-A75A-DE909711B481

Q41330743-58B851F0-3B8C-40FF-8178-CD27CB2CC4FA

Q41330743-8425173D-805D-4F7D-B121-6A41CB101380

Q41330743-8F5D3B35-45F3-4E0C-8757-333B1DACD545

Q41330743-904227DD-844A-4308-8EED-303BB873A184

Q41330743-B3EB4DB0-6F1E-4A1B-B607-C5D61B8C5AF9

Q41330743-C4C266AA-536F-4305-A506-1893EB3006F8

Q41330743-EB8B32E3-D6AE-4E99-9809-C83000C101D7

P2860

Q41330743-07571673-2B15-4B96-87F8-9952AC3D7A4B

Q41330743-090C5A6A-4B20-4CE7-9AC5-E8E2B00FDA92

Q41330743-14E266E9-4D2F-4F46-9CD3-8DDF28150E98

Q41330743-17741218-132A-4977-BA51-049AF8E4087B

Q41330743-1CAA927C-242A-4F0B-992D-FBAD1D33DE0E

Q41330743-203246C4-9993-4633-A0B1-90D95C368592

Q41330743-2DE44048-C6A2-4032-8DA5-963CAAABCE86

Q41330743-2FE39FD8-20FD-475C-B8A5-FC8588CCF48E

Q41330743-37A47119-74CD-4BC3-AB9B-E87D56247C81

Q41330743-4C269EFB-B922-4995-B782-2AA4005F80B0

P304

Q41330743-8252515C-303A-4B4C-B2BE-895E99C663BA

P31

Q41330743-8ECCBFA0-2391-46C2-A4C9-4A5D09960599

P356

Q41330743-8E230962-CAD6-43E4-B211-E0A3C4E77995

P407

Q41330743-3C903D1A-231F-41AB-A9DD-73D921AFE5E9

P433

Q41330743-232A9574-0923-4600-A087-2823E2F86EBC

P478

Q41330743-676E1AFB-AC10-4D77-8A5A-F1A3CF65CB11

P50

Q41330743-4EFBED79-4591-4D61-9CDF-9AE5263EF1E9

Q41330743-700AEF56-4112-496B-9308-D8435B78CD5F

P577

Q41330743-A4C18EA8-2208-4BE6-A8FE-175FC182761E

P5875

Q41330743-C8CE7A1E-A0E2-4233-A752-D2F411E416A0

P698

Q41330743-5E3FB32F-41C8-47F6-A7B1-80FC371A15D7

P932

Q41330743-6DD3389D-640E-4502-B9E6-5E29F2DE4040

P356

P1433

Journal of Experimental Medicine

P1476

Prostaglandin E2 regulates Th1 ...... nd EP2/EP4 receptor signaling.

@en

P2093

Brent S McKenzie

http://www.w3.org/2001/XMLSchema#string

Daniel J Cua

http://www.w3.org/2001/XMLSchema#string

Kristian S Bak-Jensen

http://www.w3.org/2001/XMLSchema#string

Mandy J McGeachy

http://www.w3.org/2001/XMLSchema#string

Robert A Kastelein

http://www.w3.org/2001/XMLSchema#string

Terrill K McClanahan

http://www.w3.org/2001/XMLSchema#string

Wendy M Blumenschein

http://www.w3.org/2001/XMLSchema#string

Ying Li

http://www.w3.org/2001/XMLSchema#string

P2860

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Transforming growth factor-beta induces development of the T(H)17 lineage

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

Development, cytokine profile and function of human interleukin 17-producing helper T cells

Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

P304

535-548

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.20082293

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

206

http://www.w3.org/2001/XMLSchema#string

P50

René de Waal Malefyt

P577

2009-03-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

24188938

http://www.w3.org/2001/XMLSchema#string

P698

19273625

http://www.w3.org/2001/XMLSchema#string

P932

2699124

http://www.w3.org/2001/XMLSchema#string