Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease.
about
Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicityPARK13 regulates PINK1 and subcellular relocation patterns under oxidative stress in neuronsThe chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicityDJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosisThe role of oxidative stress in Parkinson's diseaseCardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complexDopamine transporter mRNA content in human substantia nigra decreases precipitously with ageUnexpected expression of alpha- and beta-globin in mesencephalic dopaminergic neurons and glial cellsAdenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry implications for drug addiction, sleep and painMouse models of Parkinson's disease associated with mitochondrial dysfunctionColloids as mobile substrates for the implantation and integration of differentiated neurons into the mammalian brainCharacterization of cognitive deficits in rats overexpressing human alpha-synuclein in the ventral tegmental area and medial septum using recombinant adeno-associated viral vectorsConverging roles of ion channels, calcium, metabolic stress, and activity pattern of Substantia nigra dopaminergic neurons in health and Parkinson's diseaseImmunomodulators as Therapeutic Agents in Mitigating the Progression of Parkinson's DiseaseParkinson's disease as a result of agingVariability in neuronal expression of dopamine receptors and transporters in the substantia nigraInteractions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's diseaseIron storage within dopamine neurovesicles revealed by chemical nano-imagingCellular localization of the Huntington's disease protein and discrimination of the normal and mutated formNurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neuronsInvolvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neuronsOrexinergic input to dopaminergic neurons of the human ventral tegmental areaA Proteomics Approach to Investigate miR-153-3p and miR-205-5p Targets in Neuroblastoma CellsPrincipal Component Analysis of Multimodal Neuromelanin MRI and Dopamine Transporter PET Data Provides a Specific Metric for the Nigral Dopaminergic Neuronal DensityThe hidden sister of motor fluctuations in Parkinson's disease: A review on nonmotor fluctuations.A new brain dopamine-deficient Drosophila and its pharmacological and genetic rescue.Dopaminergic Neurodegeneration in the Mouse Is Associated with Decrease of Viscoelasticity of Substantia Nigra Tissue.High-frequency stimulation of the subthalamic nucleus counteracts cortical expression of major histocompatibility complex genes in a rat model of Parkinson's disease.Decomposition of abnormal free locomotor behavior in a rat model of Parkinson's diseaseHeterogeneous dopamine populations project to specific subregions of the primate amygdala.Genetic dissection of midbrain dopamine neuron development in vivo.Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's diseaseSynthesis and structural characterization of soluble neuromelanin analogs provides important clues to its biosynthesis.Differential effects of intrastriatal 6-hydroxydopamine on cell number and morphology in midbrain dopaminergic subregions of the ratLack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression.Alpha-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease.7 Tesla magnetic resonance imaging: a closer look at substantia nigra anatomy in Parkinson's disease.Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protectionIron-melanin complex in substantia nigra of parkinsonian brains: an x-ray microanalysis.An endogenous serine/threonine protein phosphatase inhibitor, G-substrate, reduces vulnerability in models of Parkinson's disease.
P2860
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P2860
Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Melanized dopaminergic neurons ...... ration in Parkinson's disease.
@en
type
label
Melanized dopaminergic neurons ...... ration in Parkinson's disease.
@en
prefLabel
Melanized dopaminergic neurons ...... ration in Parkinson's disease.
@en
P2093
P356
P1433
P1476
Melanized dopaminergic neurons ...... ration in Parkinson's disease.
@en
P2093
P2888
P304
P356
10.1038/334345A0
P407
P577
1988-07-01T00:00:00Z
P6179
1052129772