Truncation of the thyrotropin-releasing hormone receptor carboxyl tail causes constitutive activity and leads to impaired responsiveness in Xenopus oocytes and AtT20 cells.

Truncation of the thyrotropin-releasing hormone receptor carboxyl tail causes constitutive activity and leads to impaired responsiveness in Xenopus oocytes and AtT20 cells.

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http://www.wikidata.org/entity/Q41379572
Cloning and sequencing of the cDNA species for mammalian dimeric dihydrodiol dehydrogenasesAgonist-independent activation of metabotropic glutamate receptors by the intracellular protein HomerComputational analysis of the CB1 carboxyl-terminus in the receptor-G protein complexConstitutive signaling by Kaposi's sarcoma-associated herpesvirus G-protein-coupled receptor desensitizes calcium mobilization by other receptors.The human B1 bradykinin receptor exhibits high ligand-independent, constitutive activity. Roles of residues in the fourth intracellular and third transmembrane domains.Inverse agonist abolishes desensitization of a constitutively active mutant of thyrotropin-releasing hormone receptor: role of cellular calcium and protein kinase C.Rapid desensitization of the TRH receptor and persistent desensitization of its constitutively active mutant.Identification and characterization of distinct C-terminal domains of the human hydroxycarboxylic acid receptor-2 that are essential for receptor export, constitutive activity, desensitization, and internalization.Distinct function of the cytoplasmic tail in human D1-like receptor ligand binding and coupling.Agonist-independent internalization and activity of a C-terminally truncated somatostatin receptor subtype 2 (delta349).Gonadotropin-releasing hormone receptors with intracellular carboxyl-terminal tails undergo acute desensitization of total inositol phosphate production and exhibit accelerated internalization kinetics.A cluster of basic residues in the carboxyl-terminal tail of the short metabotropic glutamate receptor 1 variants impairs their coupling to phospholipase C.Truncation of the C-terminal tail of the follitropin receptor does not impair the agonist- or phorbol ester-induced receptor phosphorylation and uncoupling.Interspecies polymorphisms confer constitutive activity to the Mastomys cholecystokinin-B/gastrin receptor.Alanine exchanges of polar amino acids in the transmembrane domains of a platelet-activating factor receptor generate both constitutively active and inactive mutants.
P2860

Truncation of the thyrotropin-releasing hormone receptor carboxyl tail causes constitutive activity and leads to impaired responsiveness in Xenopus oocytes and AtT20 cells.

Item
http://www.wikidata.org/entity/Q41379572
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Truncation of the thyrotropin- ...... nopus oocytes and AtT20 cells.
@en
type
label
Truncation of the thyrotropin- ...... nopus oocytes and AtT20 cells.
@en
prefLabel
Truncation of the thyrotropin- ...... nopus oocytes and AtT20 cells.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P356
P1433
P1476
Truncation of the thyrotropin- ...... nopus oocytes and AtT20 cells.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698