Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.
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Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors.Short-lived long non-coding RNAs as surrogate indicators for chemical exposure and LINC00152 and MALAT1 modulate their neighboring genesNuclear RNA Decay Pathways Aid Rapid Remodeling of Gene Expression in Yeast.ARS2 is a general suppressor of pervasive transcriptionAn Mtr4/ZFC3H1 complex facilitates turnover of unstable nuclear RNAs to prevent their cytoplasmic transport and global translational repression.Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing.Exosome cofactor hMTR4 competes with export adaptor ALYREF to ensure balanced nuclear RNA pools for degradation and export.Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage.Transcriptional Pause Sites Delineate Stable Nucleosome-Associated Premature Polyadenylation Suppressed by U1 snRNP.YTH-RNA-binding protein prevents deleterious expression of meiotic proteins by tethering their mRNAs to nuclear foci.RNA helicases in RNA decay.Mtr4/ZFC3H1 protects polysomes through nuclear RNA surveillance.RNA surveillance by the nuclear RNA exosome: mechanisms and significance.Nuclear RNA surveillance complexes silence HIV-1 transcription.Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting.The RNA Exosome Adaptor ZFC3H1 Functionally Competes with Nuclear Export Activity to Retain Target Transcripts.Structural basis for MTR4-ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex.Surveillance-ready transcription: nuclear RNA decay as a default fate.Distinct and evolutionary conserved structural features of the human nuclear exosome complexNRDE-2, the human homolog of fission yeast Nrl1, prevents DNA damage accumulation in human cellsDiminished nuclear RNA decay upon infection upregulates antibacterial noncoding RNAsHelicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 ComplexInvestigation of RNA Synthesis Using 5-Bromouridine Labelling and ImmunoprecipitationSequence Determinants for Nuclear Retention and Cytoplasmic Export of mRNAs and lncRNAsThe splicing factor SRSF3 is functionally connected to the nuclear RNA exosome for intronless mRNA decayLong noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast
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P2860
Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.
@en
type
label
Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.
@en
prefLabel
Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.
@en
P2093
P50
P1433
P1476
Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.
@en
P2093
Coline Gentil
Dennis Pultz
Evdoxia Karadoulama
Jens S Andersen
Michal Domanski
Nicola Meola
P304
P356
10.1016/J.MOLCEL.2016.09.025
P577
2016-10-27T00:00:00Z