Preliminary efficacy, safety, pharmacokinetics, pharmacodynamics and quality of life study of pegylated recombinant human arginase 1 in patients with advanced hepatocellular carcinoma.

Preliminary efficacy, safety, pharmacokinetics, pharmacodynamics and quality of life study of pegylated recombinant human arginase 1 in patients with advanced hepatocellular carcinoma.

Item
http://www.wikidata.org/entity/Q41457918
Growth suppressive effect of pegylated arginase in malignant pleural mesothelioma xenografts.Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target.Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation.Arginine auxotrophic gene signature in paediatric sarcomas and brain tumours provides a viable target for arginine depletion therapies.The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100.Metabolomic profiling identifies distinct phenotypes for ASS1 positive and negative GBM.Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases.Metabolic therapy with PEG-arginase induces a sustained complete remission in immunotherapy-resistant melanoma.Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responsesRecombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancerSensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes
P2860

Preliminary efficacy, safety, pharmacokinetics, pharmacodynamics and quality of life study of pegylated recombinant human arginase 1 in patients with advanced hepatocellular carcinoma.

Item
http://www.wikidata.org/entity/Q41457918
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Preliminary efficacy, safety, ...... nced hepatocellular carcinoma.
@en
type
label
Preliminary efficacy, safety, ...... nced hepatocellular carcinoma.
@en
prefLabel
Preliminary efficacy, safety, ...... nced hepatocellular carcinoma.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P6179
P698
P356
P1433
P1476
Preliminary efficacy, safety, ...... nced hepatocellular carcinoma.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P6179
P698