Activation of the alpha 4 beta 1 integrin through the beta 1 subunit induces recognition of the RGDS sequence in fibronectin.
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Bone marrow stromal cells protect lymphoma B-cells from rituximab-induced apoptosis and targeting integrin α-4-β-1 (VLA-4) with natalizumab can overcome this resistancePhosphoinositide 3-kinase p85beta regulates invadopodium formation.Alpha4beta1 integrin/ligand interaction inhibits alpha5beta1-induced stress fibers and focal adhesions via down-regulation of RhoA and induces melanoma cell migration.The pathophysiologic role of alpha 4 integrins in vivoIntegrin alpha 8 beta 1 promotes attachment, cell spreading, and neurite outgrowth on fibronectinFibronectin-mononuclear cell interactions regulate type 1 helper T cell cytokine network in tolerant transplant recipients.Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin.Expression of the alpha 5 beta 1 fibronectin receptor on T lymphocytes of patients with HIV-1 infection.Beta 1 integrins mediate adherent phenotype of human erythroblastic cell lines after phorbol 12-myristate 13-acetate induction.Marine-derived oligosaccharide sulfate (JG3) suppresses heparanase-driven cell adhesion events in heparanase over-expressing CHO-K1 cells.Functional and selective targeting of adenovirus to high-affinity Fcgamma receptor I-positive cells by using a bispecific hybrid adapterApoptotic death of hematopoietic tumor cells through potentiated and sustained adhesion to fibronectin via VLA-4Multiple binding sites in fibrinogen for integrin alphaMbeta2 (Mac-1).LPAM-1 (integrin alpha 4 beta 7)-ligand binding: overlapping binding sites recognizing VCAM-1, MAdCAM-1 and CS-1 are blocked by fibrinogen, a fibronectin-like polymer and RGD-like cyclic peptides.Fibronectin type III5 repeat contains a novel cell adhesion sequence, KLDAPT, which binds activated alpha4beta1 and alpha4beta7 integrins.Requirement for the synergy site for cell adhesion to fibronectin depends on the activation state of integrin alpha 5 beta 1.Mutations in the heparin binding domain of fibronectin in cooperation with the V region induce decreases in pp125(FAK) levels plus proteoglycan-mediated apoptosis via caspases.Matrix metalloproteinase-2-deficient fibroblasts exhibit an alteration in the fibrotic response to connective tissue growth factor/CCN2 because of an increase in the levels of endogenous fibronectin.Integrin signalling regulates the nuclear localization and function of the lysophosphatidic acid receptor-1 (LPA1) in mammalian cells.Asp-698 and Asp-811 of the integrin alpha4-subunit are critical for the formation of a functional heterodimer.A synthetic peptide from the heparin-binding domain III (repeats III4-5) of fibronectin promotes stress-fibre and focal-adhesion formation in melanoma cells.Mechanism of CD47-induced alpha4beta1 integrin activation and adhesion in sickle reticulocytes.Combined 1H-NMR and molecular dynamics studies on conformational behavior of a model heptapeptide, GRGDSPC.Role of two conserved glycine residues in the beta-propeller domain of the integrin alpha4 subunit in VLA-4 conformation and function.Fibulin-5 regulates keloid-derived fibroblast-like cells through integrin beta-1.Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin functionCooperative Role for Activated α4β1 Integrin and Chondroitin Sulfate Proteoglycans in Cell Adhesion to the Heparin III Domain of FibronectinAnalysis of the activation state of α4β1 integrin in human B cell lines derived from myeloma, leukemia or lymphomaThe α4β1 Fibronectin Ligands CS-19 HEP II, and RGD Induce Different Intracellular Events in B Lymphoid Cells. Comparison with the Effects of the Endothelial Ligand V CAM-1
P2860
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P2860
Activation of the alpha 4 beta 1 integrin through the beta 1 subunit induces recognition of the RGDS sequence in fibronectin.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Activation of the alpha 4 beta ...... RGDS sequence in fibronectin.
@en
type
label
Activation of the alpha 4 beta ...... RGDS sequence in fibronectin.
@en
prefLabel
Activation of the alpha 4 beta ...... RGDS sequence in fibronectin.
@en
P2093
P2860
P356
P1476
Activation of the alpha 4 beta ...... RGDS sequence in fibronectin.
@en
P2093
Dominguez-Jiménez C
Garcia-Pardo A
Sánchez-Aparicio P
P2860
P304
P356
10.1083/JCB.126.1.271
P407
P577
1994-07-01T00:00:00Z