Notch and TGFβ form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity. - Wikidata - wikimedia - TriplyDB

Notch and TGFβ form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity.

Notch and TGFβ form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity.

http://www.wikidata.org/entity/Q41464948

about

Notch signaling in prostate cancer: refining a therapeutic opportunity Notch signaling in prostate cancer: a moving target Aberrant Transforming Growth Factor-β Activation Recruits Mesenchymal Stem Cells During Prostatic Hyperplasia.Hedgehog signaling in prostate epithelial-mesenchymal growth regulation.The Lin28/let-7 axis is critical for myelination in the peripheral nervous system.Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer.New insights into prostate cancer stem cells Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation.Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer.Ossifying fibroma tumor stem cells are maintained by epigenetic regulation of a TSP1/TGF-β/SMAD3 autocrine loop.Beyond the niche: tissue-level coordination of stem cell dynamics.The essential role of GATA transcription factors in adult murine prostate.Dual tumor suppressing and promoting function of Notch1 signaling in human prostate cancer.Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin.Lgr4 is a key regulator of prostate development and prostate stem cell differentiation.Tumor-suppressive activity of Lunatic Fringe in prostate through differential modulation of Notch receptor activation.Cells of origin for cancer: an updated view from prostate cancer.Notch signaling in the prostate: critical roles during development and in the hallmarks of prostate cancer biology.HES6 promotes prostate cancer aggressiveness independently of Notch signalling.Notch1 stimulation induces a vascularization switch with pericyte-like cell differentiation of glioblastoma stem cells.Morphoregulatory pathways in prostate ductal development.Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model Stem Cell Antigen-1 Identifies a Distinct Androgen-Independent Murine Prostatic Luminal Cell Lineage with Bipotent Potential.Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer.Multipotent Basal Stem Cells, Maintained in Localized Proximal Niches, Support Directed Long-Ranging Epithelial Flows in Human Prostates.Increased Notch signalling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells.Notch signaling dynamics in the adult healthy prostate and in prostatic tumor development.Desquamation takes center stage at the origin of proliferative inflammatory atrophy, epithelial-mesenchymal transition, and stromal growth in benign prostate hyperplasia.Migration of smooth muscle cells from the arterial anastomosis of arteriovenous fistulas requires Notch activation to form neointima.The dual nature of Notch in tissue homeostasis and carcinogenesis.Histone 2B-GFP Label-Retaining Prostate Luminal Cells Possess Progenitor Cell Properties and Are Intrinsically Resistant to Castration.Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.TGFβ signaling limits lineage plasticity in prostate cancer.

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P2860

Notch and TGFβ form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity.

http://www.wikidata.org/entity/Q41464948

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Notch and TGFβ form a reciproc ...... stem/progenitor cell activity.

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Notch and TGFβ form a reciproc ...... stem/progenitor cell activity.

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Notch and TGFβ form a reciproc ...... stem/progenitor cell activity.

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J.STEM.2012.07.003

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P1476

Notch and TGFβ form a reciproc ...... stem/progenitor cell activity.

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P2093

Chad J Creighton

http://www.w3.org/2001/XMLSchema#string

David M Spencer

http://www.w3.org/2001/XMLSchema#string

Joseph M Valdez

http://www.w3.org/2001/XMLSchema#string

Li Xin

http://www.w3.org/2001/XMLSchema#string

Li Zhang

http://www.w3.org/2001/XMLSchema#string

Michael M Ittmann

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Olga Dakhova

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Payam Shahi

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Qingtai Su

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Yiqun Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

Notch signalling regulates stem cell numbers in vitro and in vivo

Direct regulation of intestinal fate by Notch

Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation

Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation

p63 is a p53 homologue required for limb and epidermal morphogenesis

High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism

The canonical Notch signaling pathway: unfolding the activation mechanism.

Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity

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676-688

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10.1016/J.STEM.2012.07.003

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5

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11

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3490134

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