Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway.
about
Recent advances in understanding neurotrophin signalingLow Density Lipoprotein Receptor Related Proteins as Regulators of Neural Stem and Progenitor Cell FunctionPhysiological and pathological roles of tissue plasminogen activator and its inhibitor neuroserpin in the nervous systemThe low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's diseaseLDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin.Valproic acid induces astrocyte-dependent neurite outgrowth from cultured rat primary cortical neuron via modulation of tPA/PAI-1 activityInflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophagesLDL receptor-related protein-1: a regulator of inflammation in atherosclerosis, cancer, and injury to the nervous systemLRP1 regulates remodeling of the extracellular matrix by fibroblasts.Low-Density Lipoprotein Receptor-Related Protein-1 Signaling in Angiogenesis.Low density lipoprotein receptor-related protein (LRP1) regulates Rac1 and RhoA reciprocally to control Schwann cell adhesion and migration.Low-density lipoprotein receptor-related protein-1 mediates endocytic clearance of tissue inhibitor of metalloproteinases-1 and promotes its cytokine-like activitiesLRP-1 promotes cancer cell invasion by supporting ERK and inhibiting JNK signaling pathwaystPA activates LDL receptor-related protein 1-mediated mitogenic signaling involving the p90RSK and GSK3beta pathwayLDL receptor-related protein 1 regulates the abundance of diverse cell-signaling proteins in the plasma membrane proteome.Apolipoprotein E in synaptic plasticity and Alzheimer's disease: potential cellular and molecular mechanisms.LRP-1: functions, signaling and implications in kidney and other diseases.Targeting cholesterol homeostasis to fight hearing loss: a new perspective.Tissue-type plasminogen activator (tPA) promotes M1 macrophage survival through p90 ribosomal S6 kinase (RSK) and p38 mitogen-activated protein kinase (MAPK) pathwayNeurotrophins regulate ApoER2 proteolysis through activation of the Trk signaling pathway.The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury.Role of LRP1 and ERK and cAMP Signaling Pathways in Lactoferrin-Induced Lipolysis in Mature Rat Adipocytes.Novel transcripts reveal a complex structure of the human TRKA gene and imply the presence of multiple protein isoforms.Low Density Lipoprotein-Receptor Related Protein 1 Is Differentially Expressed by Neuronal and Glial Populations in the Developing and Mature Mouse Central Nervous System.Tissue-type plasminogen activator suppresses activated stellate cells through low-density lipoprotein receptor-related protein 1Tissue plasminogen activator activates NF-κB through a pathway involving annexin A2/CD11b and integrin-linked kinase.The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration.Mesenchymal Stromal Cells Promote Axonal Outgrowth Alone and Synergistically with Astrocytes via tPASecreted Hsp90 is a novel regulator of the epithelial to mesenchymal transition (EMT) in prostate cancer.Low-density Lipoprotein Receptor-related Proteins in a Novel Mechanism of Axon Guidance and Peripheral Nerve RegenerationLipoprotein receptors--an evolutionarily ancient multifunctional receptor family.LDL receptor-related protein-1 regulates NFκB and microRNA-155 in macrophages to control the inflammatory response.Regulation of cytokine expression by Schwann cells in response to α2-macroglobulin binding to LRP1.Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes.Low-density lipoprotein receptor-related protein 1 (LRP1)-dependent cell signaling promotes axonal regeneration.Low-density lipoprotein receptor related protein-1 (LRP1)-dependent cell signaling promotes neurotrophic activity in embryonic sensory neurons.LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.Schwann cell LRP1 regulates remak bundle ultrastructure and axonal interactions to prevent neuropathic pain.Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemiaMicroparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis.
P2860
Q26740307-DAF140E0-E4A3-4DEE-BA7E-7075A9B1F461Q26767500-4A1FABC5-0CD8-402C-9E2A-7635C176036FQ26777276-8D7E4AC7-4A40-44CE-B8A8-66AC652D787DQ26827353-5D7C58F8-14FD-4A25-9121-7A725EDE21CCQ28571064-BB960885-F7B4-4645-9679-FF889B6F690FQ28581097-520B4F26-ED2E-4E5C-8DBB-810F89FEF6E2Q28585168-F0925758-7C55-441A-96FA-BA0835324197Q30408735-C21E21B2-BA1C-43D1-841B-15C1312C39C9Q33636162-7580C02D-9852-449F-AED8-04BC04B58A2FQ33710801-2732D223-734E-4251-8F8E-C94C8370D4C2Q33824976-E69B79DD-B9B3-4D50-8AF3-95E927EBBADAQ33975531-DF498F9D-23D2-45FB-8520-E6711BD30511Q33996198-04756954-A013-4BA0-96BF-12A47A6FF767Q34162322-00F5FBC3-8D1F-4326-B8CF-0F5FF2A0E0A3Q34380517-1196A012-ABDD-43BA-8419-B28614D03660Q34628212-0E43CD75-72EC-4289-8555-BA8DACEB26BFQ34835060-3D749249-71F6-44F6-B75A-CF68517B1298Q35025997-8B7457C9-66ED-4AEC-88A5-2735B21C8BBAQ35199467-ACF3CD4D-42B7-46E2-BFAD-07670AC44C6AQ35262436-B105494E-92DA-4319-812D-9D45494AB97DQ35283038-6CC48C3A-8767-403A-808D-82AA316405D7Q35823006-FA0AF3CC-7FAA-42B6-870D-C32DB9D3CCF9Q35845700-84EF6685-8A1C-4139-8432-6C53AEF87667Q36046612-60C9C6E3-3ABA-4C77-9994-9B19DF81EEC1Q36101672-57E8EC42-88CA-4901-97E1-90BA3DB6F8ADQ36109173-466E8061-6EEC-4FC1-9020-69351DD88FEDQ36125572-509C02CD-053A-43DB-98B8-BCCC6C613E44Q36222296-66EAC783-0F3C-4247-BF98-AD9A5B2513CAQ36368188-181C6710-6B9A-4C79-AFCD-438A9CD23227Q36466120-6B0EC1AD-4412-4B84-AC61-5F03803E69ECQ36486210-347A67B5-F714-42AA-B4FA-B884FFBD33CDQ36563361-D8365F52-9920-4F5D-86B1-BE4C3FDE2F8EQ36578185-B0E0FA8F-3A06-486C-B809-1D0341CF13D2Q37048447-51DDA021-49A6-4262-B7A8-2128CAB0704FQ37168384-445CC17F-E2AB-4537-8767-931854210BB1Q37192393-F3182CEF-1E12-4617-9704-506904A42050Q37333802-1142A12E-8DEB-487E-BDD2-4251C4C2BEC2Q37335259-9B754111-A3C6-4A8C-B9AA-EB89B6EEAFF4Q37352120-60C89B98-9947-4A4C-B557-762B1929A616Q37606429-A00D50C0-C368-452B-BFCD-5BE96E0D9A32
P2860
Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Ligand binding to LRP1 transac ...... mily kinase-dependent pathway.
@en
type
label
Ligand binding to LRP1 transac ...... mily kinase-dependent pathway.
@en
prefLabel
Ligand binding to LRP1 transac ...... mily kinase-dependent pathway.
@en
P2093
P2860
P1433
P1476
Ligand binding to LRP1 transac ...... amily kinase-dependent pathway
@en
P2093
Steven L Gonias
W Marie Campana
P2860
P356
10.1126/SCISIGNAL.2000188
P577
2009-04-28T00:00:00Z