about
Long-term culture of genome-stable bipotent stem cells from adult human liverMaintenance of Hepatic Functions in Primary Human Hepatocytes Cultured on Xeno-Free and Chemical Defined Human Recombinant LamininsIdentification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3)Transport, Metabolism, and Hepatotoxicity of Flutamide, Drug–Drug Interaction with Acetaminophen Involving Phase I and Phase II MetabolitesBrusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2.Primary cultures of human hepatocytes but not HepG2 hepatoblastoma cells are suitable for the study of glycosidic conjugation of bile acids.GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response.ATPase Class I Type 8B Member 1 and protein kinase C zeta induce the expression of the canalicular bile salt export pump in human hepatocytes.Metabolism of 17alpha-hydroxyprogesterone caproate, an agent for preventing preterm birth, by fetal hepatocytes.A novel bile acid-activated vitamin D receptor signaling in human hepatocytes.In situ characterization of intrahepatic non-parenchymal cells in PSC reveals phenotypic patterns associated with disease severity.New potential cell source for hepatocyte transplantation: discarded livers from metabolic disease liver transplants.Potency of individual bile acids to regulate bile acid synthesis and transport genes in primary human hepatocyte cultures.Mice with chimeric livers are an improved model for human lipoprotein metabolismInsulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: roles of forkhead box O1 and sterol regulatory element-binding protein 1c.Improved cryopreservation of human hepatocytes using a new xeno free cryoprotectant solution.Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- miceRegulation of CYP3A4 and CYP2B6 expression by liver X receptor agonists.Present status and perspectives of cell-based therapies for liver diseases.Hepatocyte transplantation: clinical experience and potential for future use.Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytesAddition of Dexamethasone Alters the Bile Acid Composition by Inducing CYP8B1 in Primary Cultures of Human Hepatocytes.Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation.De Novo Donor-Specific HLA Antibody Formation in Two Patients With Crigler-Najjar Syndrome Type I Following Human Hepatocyte Transplantation With Partial Hepatectomy Preconditioning.Production of hepatocyte-like cells from human amnion.Hepatocyte transplantation for inherited metabolic diseases of the liver.Physiological differences between human and rat primary hepatocytes in response to liver X receptor activation by 3-[3-[N-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride (GW3965).In vitro evaluation of major in vivo drug metabolic pathways using primary human hepatocytes and HepaRG cells in suspension and a dynamic three-dimensional bioreactor system.Hepatocyte transplantation improves phenotype and extends survival in a murine model of intermediate maple syrup urine disease.Differentiation and transplantation of human embryonic stem cell-derived hepatocytes.Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers.Metabolism of 4 beta -hydroxycholesterol in humans.Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.Comparison of culture media for bile Acid transport studies in primary human hepatocytes.Overexpression of cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis.Hypothermic storage of human hepatocytes for transplantation.Development and application of purified tissue dissociation enzyme mixtures for human hepatocyte isolation.Long term cultures of primary human hepatocytes as an alternative to drug testing in animals.Human pregnane X receptor activation and CYP3A4/CYP2B6 induction by 2,3-oxidosqualene:lanosterol cyclase inhibition.
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Ewa C Ellis
@ast
Ewa C Ellis
@en
Ewa C Ellis
@es
Ewa C Ellis
@nl
Ewa C Ellis
@sl
type
label
Ewa C Ellis
@ast
Ewa C Ellis
@en
Ewa C Ellis
@es
Ewa C Ellis
@nl
Ewa C Ellis
@sl
prefLabel
Ewa C Ellis
@ast
Ewa C Ellis
@en
Ewa C Ellis
@es
Ewa C Ellis
@nl
Ewa C Ellis
@sl
P1053
D-5370-2014
P106
P21
P31
P3829
P496
0000-0002-3057-5337