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Genomic Minimalism in the Early Diverging Intestinal Parasite Giardia lambliaThe P-glycoprotein inhibitor GF120918 modulates Ca2+-dependent processes and lipid metabolism in Toxoplasma gondiiThe proteome landscape of Giardia lamblia encystationAn Interactome-Centered Protein Discovery Approach Reveals Novel Components Involved in Mitosome Function and Homeostasis in Giardia lambliaProtein Import, Replication, and Inheritance of a Vestigial MitochondrionSuccess and virulence in Toxoplasma as the result of sexual recombination between two distinct ancestries.Dual acylation accounts for the localization of {alpha}19-giardin in the ventral flagellum pair of Giardia lamblia.A contiguous compartment functions as endoplasmic reticulum and endosome/lysosome in Giardia lamblia.Genome-wide analysis of gene expression and protein secretion of Babesia canis during virulent infection identifies potential pathogenicity factors.The use of light- and electron microscopy for studies on the cell- and molecular biology of parasites and parasitic diseases.Release of metabolic enzymes by Giardia in response to interaction with intestinal epithelial cellsIdentification of nucleoli in the early branching protist Giardia duodenalis.Selective condensation drives partitioning and sequential secretion of cyst wall proteins in differentiating Giardia lamblia.The antigenic composition of Neospora caninum.Glucosylceramide synthesis inhibition affects cell cycle progression, membrane trafficking, and stage differentiation in Giardia lamblia.The transcriptional response to encystation stimuli in Giardia lamblia is restricted to a small set of genes.Post-transcriptional repair of a split heat shock protein 90 gene by mRNA trans-splicing.Mitosomes in trophozoites and cysts of the reptilian parasite Entamoeba invadensThe secretory apparatus of an ancient eukaryote: protein sorting to separate export pathways occurs before formation of transient Golgi-like compartmentsA conserved stem-loop structure in the 3' untranslated region of procyclin mRNAs regulates expression in Trypanosoma brucei.Asexual expansion of Toxoplasma gondii merozoites is distinct from tachyzoites and entails expression of non-overlapping gene families to attach, invade, and replicate within feline enterocytes.RNA Seq analysis of the Eimeria tenella gametocyte transcriptome reveals clues about the molecular basis for sexual reproduction and oocyst biogenesisProteomics of secretory and endocytic organelles in Giardia lambliaClathrin-dependent pathways and the cytoskeleton network are involved in ceramide endocytosis by a parasitic protozoan, Giardia lambliaBax function in the absence of mitochondria in the primitive protozoan Giardia lambliaSecretory protein trafficking in Giardia intestinalis.Static Clathrin Assemblies at the Peripheral Vacuole-Plasma Membrane Interface of the Parasitic Protozoan Giardia lamblia.Lipid biology of Apicomplexa: perspectives for new drug targets, particularly for Toxoplasma gondii.Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds.Rac Regulates Giardia lamblia Encystation by Coordinating Cyst Wall Protein Trafficking and Secretion.Host cell P-glycoprotein is essential for cholesterol uptake and replication of Toxoplasma gondii.Cyst-Wall-Protein-1 is fundamental for Golgi-like organelle neogenesis and cyst-wall biosynthesis in Giardia lambliaMembrane trafficking and organelle biogenesis in Giardia lamblia: use it or lose it.Discovery of a tyrosine-rich sporocyst wall protein in Eimeria tenella.Serotonin regulates amylase secretion and acinar cell damage during murine pancreatitis.In vitro efficacy of bumped kinase inhibitors against Besnoitia besnoiti tachyzoites.A druggable secretory protein maturase of Toxoplasma essential for invasion and egress.The merozoite-specific protein, TgGRA11B, identified as a component of the Toxoplasma gondii parasitophorous vacuole in a tachyzoite expression model.Ablation of the single dynamin of T. brucei blocks mitochondrial fission and endocytosis and leads to a precise cytokinesis arrest.Serotonin promotes acinar dedifferentiation following pancreatitis-induced regeneration in the adult pancreas.
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hulumtues
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հետազոտող
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Adrian B. Hehl
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Adrian B. Hehl
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Adrian B. Hehl
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Adrian B. Hehl
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Adrian B. Hehl
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Adrian B. Hehl
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Adrian B. Hehl
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Adrian B. Hehl
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Adrian B. Hehl
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P106
P1153
6603965734
P21
P31
P496
0000-0002-2110-4445