The CAG/polyglutamine tract diseases: gene products and molecular pathogenesis.
about
Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tractNew 5'-(CGG)n-3' repeats in the human genomeLentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia.The expansion of amino-acid repeats is not associated to adaptive evolution in mammalian genesMultiple system atrophy: a sporadic synucleinopathy.The molecular biology of the autosomal-dominant cerebellar ataxias.Molecular clearance of ataxin-3 is regulated by a mammalian E4An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseasesThe selective vulnerability of nerve cells in Huntington's disease.Somatic instability of the DNA sequences encoding the polymorphic polyglutamine tract of the AIB1 gene.The paradigm of Huntington's disease: therapeutic opportunities in neurodegeneration.UBE4B: a promising regulatory molecule in neuronal death and survival.Androgen receptor polyglutamine repeat number: models of selection and disease susceptibility.A Tale of Two Maladies? Pathogenesis of Depression with and without the Huntington's Disease Gene Mutation.Cellular stress responses in protein misfolding diseasesAdvances in Sequencing Technologies for Understanding Hereditary Ataxias: A Review.Nanoparticulate strategies for the treatment of polyglutamine diseases by halting the protein aggregation process.Immunogenicity of P/Q-type calcium channel in small cell lung cancer: investigation of alpha1 subunit polyglutamine expansion.Intracellular processing and toxicity of the truncated androgen receptor: nuclear congophilia-associated cell death.Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro.Caffeine and adenosine A(2A) receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado-Joseph disease.Prediction of proteasome cleavage motifs by neural networks.Molecular diagnosis of Huntington disease in Brazilian patients.Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1.Intrinsic Disorder in Proteins with Pathogenic Repeat Expansions.Inhibition of Polyglutamine Protein Aggregation and Cell Death by Novel Peptides Identified by Phage Display ScreeningTransformation between α-helix and β-sheet structures of one and two polyglutamine peptides in explicit water molecules by replica-exchange molecular dynamics simulations
P2860
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P2860
The CAG/polyglutamine tract diseases: gene products and molecular pathogenesis.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The CAG/polyglutamine tract diseases: gene products and molecular pathogenesis.
@en
type
label
The CAG/polyglutamine tract diseases: gene products and molecular pathogenesis.
@en
prefLabel
The CAG/polyglutamine tract diseases: gene products and molecular pathogenesis.
@en
P2860
P1433
P1476
The CAG/polyglutamine tract diseases: gene products and molecular pathogenesis.
@en
P2093
P2860
P304
P356
10.1111/J.1750-3639.1997.TB00894.X
P50
P577
1997-07-01T00:00:00Z