Peroxisome-generated hydrogen peroxide as important mediator of lipotoxicity in insulin-producing cells.
about
Effects of the novel mitochondrial protein mimitin in insulin-secreting cellsAutophagic degradation of peroxisomes in mammalsPeroxisomes in brain development and functionRedox homeostasis in pancreatic β cellsRedox interplay between mitochondria and peroxisomesMangiferin modulation of metabolism and metabolic syndrome.Endogenous catalase delays high-fat diet-induced liver injury in mice.Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activationReactive oxygen species and redox compartmentalizationHeterozygous SOD2 deletion impairs glucose-stimulated insulin secretion, but not insulin action, in high-fat-fed mice.Catalase deletion promotes prediabetic phenotype in mice.Epidermal fatty acid-binding protein protects nerve growth factor-differentiated PC12 cells from lipotoxic injuryMechanistic insights into pancreatic beta-cell mass regulation by glucose and free fatty acids.Development of diabetes in lean Ncb5or-null mice is associated with manifestations of endoplasmic reticulum and oxidative stress in beta cells.SIRT3 Overexpression Attenuates Palmitate-Induced Pancreatic β-Cell Dysfunction.Catalase deficiency accelerates diabetic renal injury through peroxisomal dysfunctionMitochondrial ROS Metabolism: 10 Years Later.Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics?A systematic review of oxidative stress and safety of antioxidants in diabetes: focus on islets and their defense.Small molecule kaempferol modulates PDX-1 protein expression and subsequently promotes pancreatic β-cell survival and function via CREB.Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.Peroxisome degradation in mammals: mechanisms of action, recent advances, and perspectivesEndothelial peroxisomal dysfunction and impaired pexophagy promotes oxidative damage in lipopolysaccharide-induced acute kidney injury.Inactivation of specific β cell transcription factors in type 2 diabetes.U-Shaped Association between Plasma Manganese Levels and Type 2 DiabetesThe Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus.Ceramide formation as a target in beta-cell survival and function.The peroxisome: an update on mysteries.Hypoxia-dependent reactive oxygen species signaling in the pulmonary circulation: focus on ion channels.Peroxisome-mitochondria interplay and disease.The role of lipid droplet formation in the protection of unsaturated fatty acids against palmitic acid induced lipotoxicity to rat insulin-producing cells.Susceptibility of brown adipocytes to pro-inflammatory cytokine toxicity and reactive oxygen species.Elevated circulating stearic acid leads to a major lipotoxic effect on mouse pancreatic beta cells in hyperlipidaemia via a miR-34a-5p-mediated PERK/p53-dependent pathway.Fluorogenic nanoreactor assembly with boosted sensing kinetics for timely imaging of cellular hydrogen peroxide.C-peptide antioxidant adaptive pathways in β cells and diabetes.Beta cell response to nutrient overload involves phospholipid remodelling and lipid peroxidation.Peroxisomal Dysfunction in Age-Related Diseases.Target acquired: Selective autophagy in cardiometabolic disease.Overexpression of peroxisome proliferator-activated receptor α in pancreatic β-cells improves glucose tolerance in diet-induced obese mice.Stimulation of β-adrenergic receptors plays a protective role via increased expression of RAF-1 and PDX-1 in hyperglycemic rat pancreatic islet (RIN-m5F) cells.
P2860
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P2860
Peroxisome-generated hydrogen peroxide as important mediator of lipotoxicity in insulin-producing cells.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Peroxisome-generated hydrogen ...... ty in insulin-producing cells.
@en
type
label
Peroxisome-generated hydrogen ...... ty in insulin-producing cells.
@en
prefLabel
Peroxisome-generated hydrogen ...... ty in insulin-producing cells.
@en
P2093
P2860
P356
P1433
P1476
Peroxisome-generated hydrogen ...... ty in insulin-producing cells.
@en
P2093
Matthias Elsner
Sigurd Lenzen
Wiebke Gehrmann
P2860
P304
P356
10.2337/DB09-1401
P407
P577
2010-10-22T00:00:00Z