What limits affinity maturation of antibodies in Xenopus--the rate of somatic mutation or the ability to select mutants?
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Antibody Affinity Maturation in Fishes-Our Current UnderstandingAntiviral immunity in amphibiansTeleost fish mount complex clonal IgM and IgT responses in spleen upon systemic viral infectionIncreased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair proteinUnique Features of Fish Immune Repertoires: Particularities of Adaptive Immunity Within the Largest Group of VertebratesThe astonishing diversity of Ig classes and B cell repertoires in teleost fishRearrangement of immunoglobulin genes in shark germ cellsAn immunoglobulin mutator that targets G.C base pairs.In vivo and in vitro studies of immunoglobulin gene somatic hypermutation.Evolution and the molecular basis of somatic hypermutation of antigen receptor genes.Error-prone DNA repair activity during somatic hypermutation in shark B lymphocytesThe immunoglobulins of cold-blooded vertebratesDiverse immunoglobulin light chain organizations in fish retain potential to revise B cell receptor specificitiesLymphocytes and macrophages outnumber oligodendroglia in normal fish spinal cord.Somatic hypermutation of the new antigen receptor gene (NAR) in the nurse shark does not generate the repertoire: possible role in antigen-driven reactions in the absence of germinal centersAfrican Lungfish Reveal the Evolutionary Origins of Organized Mucosal Lymphoid Tissue in Vertebrates.Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection.Comparative and developmental study of the immune system in Xenopus.Genetic plasticity of V genes under somatic hypermutation: statistical analyses using a new resampling-based methodology.Immunoglobulin light chain (IgL) genes in zebrafish: Genomic configurations and inversional rearrangements between (V(L)-J(L)-C(L)) gene clusters.B cell function in mice transgenic for mCTLA4-H gamma 1: lack of germinal centers correlated with poor affinity maturation and class switching despite normal priming of CD4+ T cells"Double-duty" conventional dendritic cells in the amphibian Xenopus as the prototype for antigen presentation to B cells.
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P2860
What limits affinity maturation of antibodies in Xenopus--the rate of somatic mutation or the ability to select mutants?
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1992 nî lūn-bûn
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1992年の論文
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1992年論文
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1992年論文
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1992年論文
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1992年論文
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1992年論文
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1992年论文
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1992年论文
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1992年论文
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What limits affinity maturatio ...... the ability to select mutants?
@en
type
label
What limits affinity maturatio ...... the ability to select mutants?
@en
prefLabel
What limits affinity maturatio ...... the ability to select mutants?
@en
P2093
P2860
P1433
P1476
What limits affinity maturatio ...... the ability to select mutants?
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P2093
P2860
P304
P407
P577
1992-12-01T00:00:00Z