about
Ca²⁺ and calpain control membrane expansion during the rapid cell spreading of neutrophils.A trick of the light: the optical properties of living cytoplasm which can mislead.Techniques for measuring and manipulating free Ca2+ in the cytosol and organelles of neutrophils.P2X7 receptor activation regulates rapid unconventional export of transglutaminase-2.Leukocyte membrane "expansion": a central mechanism for leukocyte extravasation.In vivo functional analysis and genetic modification of in vitro-derived mouse neutrophils.A reporter of UV intensity delivered to the cytosol during photolytic uncaging.Exclusion of exogenous phosphatidylinositol-3,4,5-trisphosphate from neutrophil-polarizing pseudopodia: stabilization of the uropod and cell polarity.Topographical interrogation of the living cell surface reveals its role in rapid cell shape changes during phagocytosis and spreading.Translocation or just location? Pseudopodia affect fluorescent signals.Minimal impact electro-injection of cells undergoing dynamic shape change reveals calpain activation.Phagosomal oxidative activity during beta2 integrin (CR3)-mediated phagocytosis by neutrophils is triggered by a non-restricted Ca2+ signal: Ca2+ controls time not space.Ca influx shutdown in neutrophils induced by Fas (CD95) cross-linking.Reduced iC3b-mediated phagocytotic capacity of pulmonary neutrophils in cystic fibrosis.Localised PtdIns(3,4,5)P3 or PtdIns(3,4)P2 at the phagocytic cup is required for both phagosome closure and Ca2+ signalling in HL60 neutrophils.Differential regulation of TROP2 release by PKC isoforms through vesicles and ADAM17.Ironing out the wrinkles of neutrophil phagocytosisChemotaxis and the cell surface-area problemOptical methods for the measurement and manipulation of cytosolic calcium signals in neutrophils
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Sharon Dewitt
@ast
Sharon Dewitt
@en
Sharon Dewitt
@es
Sharon Dewitt
@nl
Sharon Dewitt
@sl
type
label
Sharon Dewitt
@ast
Sharon Dewitt
@en
Sharon Dewitt
@es
Sharon Dewitt
@nl
Sharon Dewitt
@sl
prefLabel
Sharon Dewitt
@ast
Sharon Dewitt
@en
Sharon Dewitt
@es
Sharon Dewitt
@nl
Sharon Dewitt
@sl
P106
P31
P496
0000-0001-8169-8241