about
RNA-programmed genome editing in human cellsATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing.Programmable RNA recognition and cleavage by CRISPR/Cas9.Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer.Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.Identification of a Minimal Peptide Tag for in Vivo and in Vitro Loading of Encapsulin.Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection.Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.RNA binding and HEPN nuclease activation are decoupled in CRISPR-Cas13a
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description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Alexandra East-Seletsky
@ast
Alexandra East-Seletsky
@en
Alexandra East-Seletsky
@es
type
label
Alexandra East-Seletsky
@ast
Alexandra East-Seletsky
@en
Alexandra East-Seletsky
@es
altLabel
Alexandra East
@en
Alexandra East-Seletsky
@en
prefLabel
Alexandra East-Seletsky
@ast
Alexandra East-Seletsky
@en
Alexandra East-Seletsky
@es
P106
P21
P31
P496
0000-0001-6673-5817