Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms.
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Individuality, phenotypic differentiation, dormancy and 'persistence' in culturable bacterial systems: commonalities shared by environmental, laboratory, and clinical microbiologyNext-generation antimicrobials: from chemical biology to first-in-class drugsNon-Invasive Microbial Metabolic Activity Sensing at Single Cell Level by Perfusion of Calcein Acetoxymethyl EsterThe Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.A critical review on ultrasensitive, spectroscopic-based methods for high-throughput monitoring of bacteria during infection treatment.Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic.Classic reaction kinetics can explain complex patterns of antibiotic action.Unexpected high prevalence of resistance-associated Rv0678 variants in MDR-TB patients without documented prior use of clofazimine or bedaquilineAntimicrobial Activity and Resistance: Influencing Factors.Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.Single-cell tracking reveals antibiotic-induced changes in mycobacterial energy metabolism.Profiling persistent tubercule bacilli from patient sputa during therapy predicts early drug efficacy.Transcriptional Adaptation of Drug-tolerant Mycobacterium tuberculosis During Treatment of Human TuberculosisA Precise Temperature-Responsive Bistable Switch Controlling Yersinia Virulence.Phenotypically Adapted Mycobacterium tuberculosis Populations from Sputum Are Tolerant to First-Line DrugsImmune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo.A Flow Cytometry Method for Rapidly Assessing Mycobacterium tuberculosis Responses to Antibiotics with Different Modes of ActionTemporal and intrinsic factors of rifampicin tolerance in mycobacteria.Elucidating population-wide mycobacterial replication dynamics at the single-cell levelThe Minimal Unit of Infection: Mycobacterium tuberculosis in the Macrophage.Regulatory (pan-)genome of an obligate intracellular pathogen in the PVC superphylum.Improving the tuberculosis drug development pipeline.Metabolic activity of mature biofilms of Mycobacterium tuberculosis and other non-tuberculous mycobacteria.A bug's life in the granuloma.Anti-virulence Strategies to Target Bacterial Infections.Defining heterogeneity within bacterial populations via single cell approaches.Mechanisms of bacterial persistence during stress and antibiotic exposure.Targeting Phenotypically Tolerant Mycobacterium tuberculosis.Development of an In Vitro Assay for Detection of Drug-Induced Resuscitation-Promoting-Factor-Dependent Mycobacteria.Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis.Differentially Culturable Tubercule Bacilli are Generated During Non-pulmonary Tuberculosis Infection.Mycobacterial DNA-binding protein 1 is critical for long term survival of Mycobacterium smegmatis and simultaneously coordinates cellular functions.Mycobacteria Modify Their Cell Size Control under Sub-Optimal Carbon Sources.Mycobacterium tuberculosis protease MarP activates a peptidoglycan hydrolase during acid stress.Polyketide Quinones Are Alternate Intermediate Electron Carriers during Mycobacterial Respiration in Oxygen-Deficient Niches.Influence of Stress and Antibiotic Resistance on Cell-Length Distribution in Mycobacterium tuberculosis Clinical Isolates.Antibiotic efficacy-context matters.Oxidation of dCTP contributes to antibiotic lethality in stationary-phase mycobacteria.Pseudomonas syringae Differentiates into Phenotypically Distinct Subpopulations During Colonization of a Plant Host.Modelling the effects of bacterial cell state and spatial location on tuberculosis treatment: Insights from a hybrid multiscale cellular automaton model.
P2860
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P2860
Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Stress and host immunity ampli ...... ng metabolically active forms.
@en
type
label
Stress and host immunity ampli ...... ng metabolically active forms.
@en
prefLabel
Stress and host immunity ampli ...... ng metabolically active forms.
@en
P1433
P1476
Stress and host immunity ampli ...... ing metabolically active forms
@en
P2093
Giulia Manina
John D McKinney
P356
10.1016/J.CHOM.2014.11.016
P50
P577
2014-12-24T00:00:00Z