about
GSK-3: tricks of the trade for a multi-tasking kinasePhosphorylation of serine 262 in the gap junction protein connexin-43 regulates DNA synthesis in cell-cell contact forming cardiomyocytesInhibition of TGFbeta signaling potentiates the FGF-2-induced stimulation of cardiomyocyte DNA synthesisPhosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted lociGSK-3alpha directly regulates beta-adrenergic signaling and the response of the heart to hemodynamic stress in miceA dual-kinase mechanism for Wnt co-receptor phosphorylation and activationAbnormalities in brain structure and behavior in GSK-3alpha mutant miceGenetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistanceEctopic γ-catenin expression partially mimics the effects of stabilized β-catenin on embryonic stem cell differentiationPrevention of amino acid conversion in SILAC experiments with embryonic stem cells.Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells.Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions.Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation.Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action.Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation.GSK-3 is a master regulator of neural progenitor homeostasis.Medulloblastoma stem cells: where development and cancer cross pathways.Medulloblastoma stem cells: modeling tumor heterogeneity.Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin PathwayInitiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines.Regulation of basic fibroblast growth factor (bFGF) and FGF receptors in the heart.Selective monoclonal antibody recognition and cellular localization of an unphosphorylated form of connexin43.Exploring pluripotency with chemical genetics.Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor-Initiating Cells.The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin.Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium.IL-17 receptor signaling inhibits C/EBPbeta by sequential phosphorylation of the regulatory 2 domain.Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism.Calcium protects pituitary basic fibroblast growth factors from limited proteolysis by co-purifying proteases.R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling.GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia.BMI1 is a therapeutic target in recurrent medulloblastomaFGF-2-induced Negative Inotropism and Cardioprotection are Inhibited by Chelerythrine: Involvement of Sarcolemmal Calcium-independent Protein Kinase CBasic fibroblast growth factor stimulates connexin-43 expression and intercellular communication of cardiac fibroblastsOver-expression of CUG- or AUG-initiated Forms of Basic Fibroblast Growth Factor in Cardiac Myocytes Results in Similar Effects on Mitosis and Protein Synthesis but Distinct Nuclear MorphologiesThe carboxy-tail of connexin-43 localizes to the nucleus and inhibits cell growthCUG-initiated FGF-2 induces chromatin compaction in cultured cardiac myocytes and in vitroCardiomyocyte gap junctions: a target of growth-promoting signalingA CD133-AKT-Wnt signaling axis drives glioblastoma brain tumor-initiating cells
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Bradley W Doble
@es
Bradley W. Doble
@en
Bradley W. Doble
@nl
Bradley W. Doble
@sl
type
label
Bradley W Doble
@es
Bradley W. Doble
@en
Bradley W. Doble
@nl
Bradley W. Doble
@sl
altLabel
Brad Doble
@en
prefLabel
Bradley W Doble
@es
Bradley W. Doble
@en
Bradley W. Doble
@nl
Bradley W. Doble
@sl
P1053
L-7551-2016
P106
P1153
6603629472
P21
P31
P3829
P496
0000-0002-0260-2983
P569
2000-01-01T00:00:00Z