The effect of bosentan on the pharmacokinetics of digoxin in healthy male subjects
about
Bosentan: a dual endothelin receptor antagonist.Clarithromycin substantially increases steady-state bosentan exposure in healthy volunteers.Clinical pharmacokinetics and drug-drug interactions of endothelin receptor antagonists in pulmonary arterial hypertension.Phase I and II metabolism and MRP2-mediated export of bosentan in a MDCKII-OATP1B1-CYP3A4-UGT1A1-MRP2 quadruple-transfected cell line.Darexaban (YM150), an oral direct factor Xa inhibitor, has no effect on the pharmacokinetics of digoxin.
P2860
The effect of bosentan on the pharmacokinetics of digoxin in healthy male subjects
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
The effect of bosentan on the pharmacokinetics of digoxin in healthy male subjects
@en
type
label
The effect of bosentan on the pharmacokinetics of digoxin in healthy male subjects
@en
prefLabel
The effect of bosentan on the pharmacokinetics of digoxin in healthy male subjects
@en
P2093
P2860
P1476
The effect of bosentan on the pharmacokinetics of digoxin in healthy male subjects
@en
P2093
P2860
P304
P356
10.1046/J.1365-2125.1999.00946.X
P407
P577
1999-06-01T00:00:00Z