Electron cryo-microscopy and image reconstruction of adeno-associated virus type 2 empty capsids.
about
Packaging capacity of adeno-associated virus serotypes: impact of larger genomes on infectivity and postentry steps.The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy.Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminusStructure of Adeno-Associated Virus Serotype 8, a Gene Therapy VectorStructural Characterization of the Dual Glycan Binding Adeno-Associated Virus Serotype 6Structural Insight into the Unique Properties of Adeno-Associated Virus Serotype 9Structural Insights into Adeno-Associated Virus Serotype 5Durable immunity to oncogenic human papillomaviruses elicited by adjuvanted recombinant Adeno-associated virus-like particle immunogen displaying L2 17-36 epitopesStructure of neurotropic adeno-associated virus AAVrh.8.Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction.Scalable downstream strategies for purification of recombinant adeno- associated virus vectors in light of the properties.Tropism-modified AAV vectors overcome barriers to successful cutaneous therapy.AAV's anatomy: roadmap for optimizing vectors for translational successStructure of adeno-associated virus type 4.Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of miceAAV and compacted DNA nanoparticles for the treatment of retinal disorders: challenges and future prospects.Glycosidic enzymes enhance retinal transduction following intravitreal delivery of AAV2.Structurally mapping the diverse phenotype of adeno-associated virus serotype 4.Receptor targeting of adeno-associated virus vectors.The assembly-activating protein promotes capsid assembly of different adeno-associated virus serotypes.Methods for gene transfer to the central nervous system.cis effects in adeno-associated virus type 2 replication.Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene TherapyIdentification of a heparin-binding motif on adeno-associated virus type 2 capsidsControlled and localized genetic manipulation in the brain.Structure of adeno-associated virus serotype 5.Evidence of prior exposure to human bocavirus as determined by a retrospective serological study of 404 serum samples from adults in the United StatesIntracellular viral processing, not single-stranded DNA accumulation, is crucial for recombinant adeno-associated virus transduction.Ocular gene delivery using lentiviral vectors.Mapping the AAV Capsid Host Antibody Response toward the Development of Second Generation Gene Delivery VectorsAdeno-associated virus structural biology as a tool in vector development.Manufacturing of recombinant adeno-associated viruses using mammalian expression platforms.Adeno-associated virus type 2 capsids with externalized VP1/VP2 trafficking domains are generated prior to passage through the cytoplasm and are maintained until uncoating occurs in the nucleus.Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging.Addition of six-His-tagged peptide to the C terminus of adeno-associated virus VP3 does not affect viral tropism or productionIdentification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding.Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions.Impact of capsid conformation and Rep-capsid interactions on adeno-associated virus type 2 genome packagingMutational analysis of narrow pores at the fivefold symmetry axes of adeno-associated virus type 2 capsids reveals a dual role in genome packaging and activation of phospholipase A2 activityHeparin binding induces conformational changes in Adeno-associated virus serotype 2.
P2860
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P2860
Electron cryo-microscopy and image reconstruction of adeno-associated virus type 2 empty capsids.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Electron cryo-microscopy and i ...... ed virus type 2 empty capsids.
@en
type
label
Electron cryo-microscopy and i ...... ed virus type 2 empty capsids.
@en
prefLabel
Electron cryo-microscopy and i ...... ed virus type 2 empty capsids.
@en
P2860
P356
P1433
P1476
Electron cryo-microscopy and i ...... ed virus type 2 empty capsids.
@en
P2093
Kleinschmidt JA
Kronenberg S
P2860
P304
P356
10.1093/EMBO-REPORTS/KVE234
P577
2001-11-01T00:00:00Z