Grapefruit juice activates P-glycoprotein-mediated drug transport.
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Medicinal importance of grapefruit juice and its interaction with various drugsSimultaneous measurement of in vivo P-glycoprotein and cytochrome P450 3A activitiesEffect of grapefruit juice on Sandimmun Neoral absorption among stable renal allograft recipients.Pharmaceuticals and personal care products in the environment: agents of subtle change?The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions.The human CYP3A subfamily: practical considerations.Drug-nutrient interactions in transplant recipients.Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation.Herbal modulation of P-glycoprotein.Mutual interactions between flavonoids and enzymatic and transporter elements responsible for flavonoid disposition via phase II metabolic pathways.Relevance of multidrug resistance proteins for intestinal drug absorption in vitro and in vivo.On the assessment of effects of food on the pharmacokinetics of drugs in early development.The effect of grapefruit juice on drug disposition.Desloratadine: a nonsedating antihistamine.The effect of food components on the absorption of P-gp substrates: a review.Intestinal drug absorption and bioavailability: beyond involvement of single transport function.ABC of oral bioavailability: transporters as gatekeepers in the gut.The effects of fruit juices on drug disposition: a new model for drug interactions.Food-drug interaction: grapefruit juice augments drug bioavailability--mechanism, extent and relevance.Complex drug interactions of the HIV protease inhibitors 3: effect of simultaneous or staggered dosing of digoxin and ritonavir, nelfinavir, rifampin, or bupropionMDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males.The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique.Top Three Pharmacogenomics and Personalized Medicine Applications at the Nexus of Renal Pathophysiology and Cardiovascular Medicine.Strategies to improve oral drug bioavailability.Grapefruit-drug interactions: can interactions with drugs be avoided?Metabolic and toxicological considerations of botanicals in anticancer therapy.Enzyme- and transporter-mediated beverage-drug interactions: An update on fruit juices and green tea.Influence of grapefruit juice on pharmacokinetics of triptolide in rats grapefruit juice on the effects of triptolide.Effect of lyophilized grapefruit juice on P-glycoprotein-mediated drug transport in-vitro and in-vivo.Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors.Plant polyphenols and multidrug resistance: effects of dietary flavonoids on drug transporters in Caco-2 and MDCKII-MDR1 cell transport models.Compound cardiac toxicity of oral erythromycin and verapamil.Lack of CYP3A4 inhibition by grapefruit juice and ketoconazole upon clozapine administration in vivo.Comparison of in vitro hepatic models for the prediction of metabolic interaction between simvastatin and naringenin.Regional transport and metabolism of ropivacaine and its CYP3A4 metabolite PPX in human intestine.Measurement of hepatic and intestinal CYP3A4 and PGP activity by combined po + iv [14C]erythromycin breath and urine test.Improved oral bioavailability of BCS class 2 compounds by self nano-emulsifying drug delivery systems (SNEDDS): the underlying mechanisms for amiodarone and talinolol.Influence of grapefruit juice on the systemic availability of itraconazole oral solution in healthy adult volunteers.Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using alfentanil and fexofenadine in combination.Effects of itraconazole or grapefruit juice on the pharmacokinetics of telithromycin.
P2860
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P2860
Grapefruit juice activates P-glycoprotein-mediated drug transport.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Grapefruit juice activates P-glycoprotein-mediated drug transport.
@en
type
label
Grapefruit juice activates P-glycoprotein-mediated drug transport.
@en
prefLabel
Grapefruit juice activates P-glycoprotein-mediated drug transport.
@en
P2093
P356
P1476
Grapefruit juice activates P-glycoprotein-mediated drug transport.
@en
P2093
Christians U
Silverman JA
P304
P356
10.1023/A:1011902625609
P577
1999-04-01T00:00:00Z