Integrin alpha 2 beta 1 is upregulated in fibroblasts and highly aggressive melanoma cells in three-dimensional collagen lattices and mediates the reorganization of collagen I fibrils.
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Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrinsFibroblasts, myofibroblasts, and wound contractionMEMD, a new cell adhesion molecule in metastasizing human melanoma cell lines, is identical to ALCAM (activated leukocyte cell adhesion molecule)Lung cancer cells that survive ionizing radiation show increased integrin α2β1- and EGFR-dependent invasivenessAttenuation of the self-renewal of transit-amplifying osteoblast progenitors in the murine bone marrow by 17 beta-estradiolThe role of alpha1beta1 integrin in wound contraction. A quantitative analysis of liver myofibroblasts in vivo and in primary cultureFunctional hierarchy of simultaneously expressed adhesion receptors: integrin alpha2beta1 but not CD44 mediates MV3 melanoma cell migration and matrix reorganization within three-dimensional hyaluronan-containing collagen matricesTraction forces mediated by alpha6beta4 integrin: implications for basement membrane organization and tumor invasion.Tumor progression, early diagnosis and prognosis of melanoma.The fibroblast integrin alpha11beta1 is induced in a mechanosensitive manner involving activin A and regulates myofibroblast differentiation.Integrins: a role as cell signalling molecules.Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicryTemporal, 3-dimensional, cellular anatomy of corneal wound tissue.Interactions of fibroblasts with the extracellular matrix: implications for the understanding of fibrosis.Mechanisms of metastasis.Cell-matrix entanglement and mechanical anchorage of fibroblasts in three-dimensional collagen matrices.Modulation of fibroblast morphology and adhesion during collagen matrix remodeling.Computational model for cell migration in three-dimensional matrices.Cell-matrix and cell-cell interactions of human gingival fibroblasts on three-dimensional nanofibrous gelatin scaffolds.Cell adhesion to extracellular matrix regulates the life cycle of integrins.Effects of interleukin-18 on cardiac fibroblast function and gene expressionThe role of extracellular matrix composition in structure and function of bioengineered skeletal muscleBone microenvironment modulates expression and activity of cathepsin B in prostate cancer.Biological evaluation of structurally diverse amaryllidaceae alkaloids and their synthetic derivatives: discovery of novel leads for anticancer drug designFibroblast expression of α-smooth muscle actin, α2β1 integrin and αvβ3 integrin: influence of surface rigidity.Understanding the final stages of wound contraction.Cdc42 regulates extracellular matrix remodeling in three dimensionsReduced granulation tissue and wound strength in the absence of α11β1 integrin.Lung fibroblast alpha-smooth muscle actin expression and contractile phenotype in bleomycin-induced pulmonary fibrosis.Distribution of integrin cell adhesion molecules in endometrial cancer.Dwarfism in mice lacking collagen-binding integrins α2β1 and α11β1 is caused by severely diminished IGF-1 levels.Decreased level of PDGF-stimulated receptor autophosphorylation by fibroblasts in mechanically relaxed collagen matrices.Tenascin-C expression by fibroblasts is elevated in stressed collagen gels.Extracellular matrix alters PDGF regulation of fibroblast integrinsPDGF induction of alpha 2 integrin gene expression is mediated by protein kinase C-zeta.Regulation of keratin and integrin gene expression in cancer and drug resistance.A three-dimensional collagen lattice induces protein kinase C-zeta activity: role in alpha2 integrin and collagenase mRNA expressionA three-dimensional collagen lattice activates NF-kappaB in human fibroblasts: role in integrin alpha2 gene expression and tissue remodeling.Stimulation of beta1 integrins on fibroblasts induces PDGF independent tyrosine phosphorylation of PDGF beta-receptors.Tyrosine phosphorylation and cytoskeletal tension regulate the release of fibroblast adhesions.
P2860
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P2860
Integrin alpha 2 beta 1 is upregulated in fibroblasts and highly aggressive melanoma cells in three-dimensional collagen lattices and mediates the reorganization of collagen I fibrils.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Integrin alpha 2 beta 1 is upr ...... ization of collagen I fibrils.
@en
type
label
Integrin alpha 2 beta 1 is upr ...... ization of collagen I fibrils.
@en
prefLabel
Integrin alpha 2 beta 1 is upr ...... ization of collagen I fibrils.
@en
P2093
P2860
P356
P1476
Integrin alpha 2 beta 1 is upr ...... ization of collagen I fibrils.
@en
P2093
Bankert RB
Steinmayer T
P2860
P304
P356
10.1083/JCB.115.5.1427
P407
P577
1991-12-01T00:00:00Z